[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604574":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":35,"locations":10,"responsibleParty":41,"collaborators":10,"id":45,"slug":10,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":10,"eligibilityCriteria":49,"healthyVolunteers":46,"sex":50,"minAge":51,"maxAge":10,"enrollmentInfo":52,"targetDuration":10,"studyType":55,"phases":10,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":65,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":10},{"fullName":5,"class":6},"Xiangya Hospital of Central South University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with traumatic brain injury and invasive ICP monitoring",null,"Patients with traumatic brain injury and invasive ICP monitoring.",[13,14,15,16],"Diagnostic Test: TCCD","Diagnostic Test: ONSD","Diagnostic Test: ODH","Diagnostic Test: Invasive ICP",[18,23,27,31],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"DIAGNOSTIC_TEST","TCCD","Patients receive non-invasive assessments of TCCD using bedside ultrasound.",[9],{"type":19,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"ONSD","Patients receive non-invasive assessments of ONSD using bedside ultrasound.",[9],{"type":19,"name":28,"description":29,"armGroupLabels":30,"otherNames":10},"ODH","Patients receive non-invasive assessments of ODH using bedside ultrasound.",[9],{"type":19,"name":32,"description":33,"armGroupLabels":34,"otherNames":10},"Invasive ICP","Patients receive invasive assessments of ICP.",[9],[36],{"name":37,"role":38,"phone":39,"phoneExt":10,"email":40},"Ziyuan Liu, M.D.","CONTACT","86-151-1137-3960","ethmery@yeah.net",{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Jinfang Liu, MD","Director of the Neurotrauma and Neurointensive Care Group","100604574",false,"NCT07151287","Diagnosis of Intracranial Hypertension Using TCCD, ONSD and ODH by Bedside Ultrasound","Inclusion Criteria:\n\n* Traumatic brain injury;\n* Received invasive ICP monitoring;\n* age ≥ 18 years old.\n\nExclusion Criteria:\n\n* Severe eyeball \u002F eyelid damage prevents transorbital ultrasound examination;\n* Allergy to ultrasound coupling agent;\n* Pregnant or lactating females.","ALL","18 Years",{"count":53,"type":54},64,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate several means of measuring intracranial pressure (ICP) non-invasively in patients who had head trauma and received implantation of invasive ICP monitor device. The main questions it aims to answer are:\n\nWhat are the diagnostic efficacies of Transcranial Color-Coded Doppler Ultrasound (TCCD), Optic Nerve Sheath Diameter (ONSD) and Optic Disc Height (ODH) (the 3 non-invasive way of measuring ICP) compared with invasive ICP monitor? Participants will receive simultaneous non-invasive measurements of TCCD, ONSD and ODH along with during the days of invasive ICP monitoring. The data will be compared among the techniques to study the diagnostic efficacy.",[58],"Traumatic Brain Injury",[60,61,62,63,64],"traumatic brain injury","craniocerebral trauma","brain trauma","intracranial pressure","transcranial Doppler ultrasound","NOT_YET_RECRUITING","2025-09-01",{"date":68,"type":69},"2025-09-03","ACTUAL",{"date":71,"type":54},"2025-09-15",{"date":73,"type":54},"2027-07-01",{"name":5,"class":6}]