Health TrialsbyHealthPanel

Distribution and Analysis of Metastatic Lymph Nodes in Colorectal Cancer Patients (DIAMOND)

ConditionsColon CancerRectal Cancer
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences

About this trial

The goal of this observational study is to learn about the spatial distribution and significance of metastatic lymph nodes in colorectal cancer patients. The main question it aims to answer is:

* What is the spatial distribution pattern of metastatic lymph nodes in patients with colorectal cancer? * Can the spatial distribution pattern of metastatic lymph nodes in patients with colorectal cancer guide clinical practice? Participants should undergo regular follow-up examinations for at least 5 years after the surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Aged between 18 and 80 years

Pathologically confirmed adenocarcinoma of the colon or rectum

Underwent radical resection for colorectal cancer with a D3 lymphadenectomy and lymph nodes were submitted for pathological examination according to standardized station-based and distance-based protocol

No distant metastasis or distant metastasis within 6 months after surgery

Disqualifiers

Pathologically confirmed benign tumors or non-adenocarcinoma malignancies

Underwent local excision or palliative resection

Regional lymph nodes were not dissected or submitted for pathological examination according to the unified station-based or distance-based protocol

With distant metastasis or distant metastasis within 6 months after surgery

Trial population

Colorectal cancer patients who undergo radical resection in the National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences, China-Japan Friendship Hospital, Shanxi Cancer Hospital, and The Affiliated Cancer Hospital of Zhengzhou University \& Henan Cancer Hospital between December 2025 and December 2027.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

1,200 Participants
are grouped into 1 trial group
Group A: Colorectal Cancer Patients

Trial outcomes

Primary outcomes

1

The spatial distribution of metastatic lymph nodes

Time frame
From enrollment to 14 days after surgery (at the completion of postoperative pathological examination)

Secondary outcomes

1

Disease-free survival

Time frame
From date of surgery until the date of first documented local recurrence, distant metastasis, or date of death from any cause, whichever came first, assessed up to 60 months
2

Overall survival

Time frame
From date of surgery until the date of death from any cause, whichever came first, assessed up to 60 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Lead sponsor

China-Japan Friendship Hospital

Collaborator

Shanxi Province Cancer Hospital

Collaborator

Zhengzhou University

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: