Dry Eye Disease With Isotretinoin ISOTRETINOIN

ConditionAcne Vulgaris

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18-40

SponsorCairo University

About this trial

The study aims to explore the effects of isotretinoin therapy on the dry eye parameters in acne vulgaris patients \& determine if it is dose-dependent or not.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Moderate to severe acne on isotretinoin

Disqualifiers

Occular diseases causing dry eye

Pregnant females

Trial population

Acne patients on isotretinoin

Trial design

Design model

Case-control

Time perspective

Cross-sectional

Treatments tested in this trial

Ocular Surface Disease Index (OSDI) questionnaire
Diagnostic test
The OSDI is a validated, self-administered questionnaire for assessing the presence and severity of ocular surface disease symptoms. The OSDI questionnaire includes 12 questions about the respondent's past week experience with the ocular symptoms, vision-related function, and environmental triggers

Treatment groups

60 Participants

are divided into 3 treatment groups

Group A: low dose isotretinoin1 intervention

Group B: high dose isotretinoin1 intervention

Group C: Normal control1 intervention

Trial outcomes

Primary outcomes

Total ocular surface disease index (OSDI) SCORE

Total OSDI score ranged from 0 to 100 with means greater symptom severity

Time frame

3 months

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Cairo University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: