[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100546272":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":36,"responsibleParty":104,"collaborators":18,"id":106,"slug":18,"hasResults":107,"nctId":108,"briefTitle":109,"officialTitle":109,"acronym":110,"eligibilityCriteria":111,"healthyVolunteers":107,"sex":112,"minAge":113,"maxAge":18,"enrollmentInfo":114,"targetDuration":18,"studyType":117,"phases":118,"briefSummary":120,"conditions":121,"keywords":18,"overallStatus":39,"whyStopped":18,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},{"fullName":5,"class":6},"Ottawa Hospital Research Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Early diagnosis of previously undiagnosed asthma or COPD","EXPERIMENTAL","On the day of randomization the participant will receive a copy of their interpreted spirometry report with a listed diagnosis. This report will be sent to their primary-care practitioner. In addition to the spirometry interpretation, the primary-care practitioner will be provided with a brief one-page guideline-based tool providing advice for pharmacologic and non-pharmacologic treatment of newly diagnosed asthma or COPD. The primary-care practitioner will be encouraged to see the participant as soon as possible to provide care. The participant will similarly be encouraged to make an appointment with the primary-care practitioner as soon as possible to access care for their condition",[13],"Other: Early diagnosis and treatment",{"label":15,"type":16,"description":17,"interventionNames":18},"Delayed diagnosis of previously undiagnosed asthma or COPD","NO_INTERVENTION","At the 12 week visit, participants randomized to the delayed diagnosis will complete the trial outcome assessments. After completing the 12 week final trial assessments they will be seen by the study respirologist and treated for their newly diagnosed asthma or COPD.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Early diagnosis and treatment","Early diagnosis of previously undiagnosed asthma or COPD and subsequent treatment by a primary care practitioner",[9],[25],{"name":26,"affiliation":5,"role":27},"Shawn Aaron, MD","PRINCIPAL_INVESTIGATOR",[29,33],{"name":26,"role":30,"phone":31,"phoneExt":18,"email":32},"CONTACT","6137378259","saaron@toh.ca",{"name":34,"role":30,"phone":31,"phoneExt":18,"email":35},"Kathy Vandemheen, MScN","kvandemheen@toh.ca",[37,58,71,87],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"St. Joseph's Hamilton Healthcare","RECRUITING","Hamilton","Ontario","L8N 4A6","Canada","CA",{"type":46,"coordinates":47},"Point",[48,49],-79.84963,43.25011,{"lat":49,"lon":48},[52,54],{"name":53,"role":30,"phone":18,"phoneExt":18,"email":18},"Andrew McIvor, MD",{"name":18,"role":30,"phone":55,"phoneExt":56,"email":57},"613-905-522-1155","35121","ljohnson@stjosham.on.ca",{"facility":59,"status":39,"city":60,"state":41,"zip":61,"country":43,"countryCode":44,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"Ottawa Hospital General Campus","Ottawa","K1H 8L6",{"type":46,"coordinates":63},[64,65],-75.69812,45.41117,{"lat":65,"lon":64},[68],{"name":69,"role":30,"phone":70,"phoneExt":18,"email":35},"Kathy Vandemheen","613-737-8259",{"facility":72,"status":39,"city":73,"state":74,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"Royal University Hospital","Saskatoon","Saskatchewan",{"type":46,"coordinates":76},[77,78],-106.66892,52.13238,{"lat":78,"lon":77},[81,83],{"name":82,"role":30,"phone":18,"phoneExt":18,"email":18},"Erika Penz, MD",{"name":84,"role":30,"phone":85,"phoneExt":18,"email":86},"Britany Duncan, MPH","(306) 966-6230","britney.duncan@usask.ca",{"facility":88,"status":39,"city":89,"state":18,"zip":90,"country":43,"countryCode":44,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"Institut universitaire de cardiologie et de pneumologie de Québec","Québec","G1V 4G5",{"type":46,"coordinates":92},[93,94],-71.21454,46.81228,{"lat":94,"lon":93},[97,99],{"name":98,"role":30,"phone":18,"phoneExt":18,"email":18},"Andréanne Côté, MD",{"name":100,"role":30,"phone":101,"phoneExt":102,"email":103},"Geneviève Parent-Racine, MSc","418-656-8711","2617","genevieve.parent-racine@criucpq.ulaval.ca",{"type":105,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100546272",false,"NCT06392776","Early Diagnosis and Treatment of Undiagnosed Asthma or COPD: THE UCAP 2 TRIAL","UCAP2","Inclusion Criteria:\n\n* Individuals at least 18 years old\n* Individuals must be symptomatic with respiratory symptoms\n* Individuals must complete the UCAP-Q questionnaire and score a ≥ 6% probability of having either asthma or COPD.\n* Individuals who have given written informed consent to participate in this trial in accordance with local regulations;\n* Individual must be able to perform pre and post bronchodilator spirometry to measure lung function\n\nAdditional Inclusion Criteria for the Randomized Controlled Trial (RCT):\n\n* Individuals who have undiagnosed airflow obstruction on spirometry testing (i.e. Asthma or COPD) will be asked to participate in the RCT.\n\nExclusion Criteria:\n\n* Individuals who report a previous diagnosis of asthma, COPD, history of lung cancer, bronchiectasis, interstitial lung disease, cystic fibrosis or other significant diagnosed lung disease.\n* Individuals currently under the care of a Respirologist.\n* Individuals currently using inhaled corticosteroids or long-acting bronchodilators.\n* Individuals with history of myocardial infarction, stroke, aortic or cerebral aneurysm, or detached retina or eye surgery within the past 3 months (spirometry is contraindicated)\n* Individuals who are in the third trimester of pregnancy\n* Individuals involved in another interventional trial","ALL","18 Years",{"count":115,"type":116},420,"ESTIMATED","INTERVENTIONAL",[119],"NA","Our research group has found that Canadians with undiagnosed asthma or chronic obstructive pulmonary disease (COPD) have increased respiratory symptoms and worse health-related quality of life.\n\nThe investigators recently developed and validated an on-line questionnaire to accurately identify these symptomatic, undiagnosed individuals.\n\nThe investigators will advertise in the community asking individuals to complete the on-line questionnaire at home, at their leisure, to determine if they are at risk of asthma or COPD. Those at risk will be invited to participate in a randomized, controlled clinical trial to determine whether early diagnosis of previously undiagnosed asthma or COPD and subsequent treatment by the primary care practitioner will improve their quality of life.",[122,123],"COPD","Asthma","2026-01-13",{"date":126,"type":127},"2026-01-14","ACTUAL",{"date":129,"type":127},"2024-07-16",{"date":131,"type":116},"2029-12",{"name":5,"class":6},4]