The study is investigating the early feasibility of a novel algorithm for a hybrid closed-loop (HCL) insulin delivery system in adult patients with Type 1 diabetes.
Participants will attend a study visit where the UBLoop system on a smartphone will manage insulin delivery via an insulin pump, using blood glucose values from a continuous glucose meter. Specialized staff and a remote monitoring system, which is integrated into the UBLoop system, will oversee the participants.
T1D diagnosis for at least one year.
Aged between 18 and 65 years old (inclusive).
Currently using insulin for at least six months.
Currently using closed-loop insulin therapy for at least three months.
An HbA1C ≥10% .
History of diabetic ketoacidosis (DKA) in the past 12 months.
History of severe hypoglycaemic event (Level 3): defined as seizure or loss of consciousness in the past 12 months.
Current uncontrolled chronic diabetic microvascular complications (neuropathy, retinopathy, renal diabetes disease, and diabetic gastroparesis).
University of Bern
Lead sponsor
DCB Research AG
Collaborator
DexCom, Inc.
Collaborator
mylife Diabetes Care AG
Collaborator