[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100316407":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":18,"centralContacts":23,"locations":29,"responsibleParty":50,"collaborators":53,"id":57,"slug":27,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":27,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":27,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":32,"whyStopped":27,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"University of Sao Paulo","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Treatment group","Early high-dose corticosteroid and immunosuppressive therapy",[12],"Drug: Early high-dose corticosteroid and immunosuppressive therapy",[14],{"type":15,"name":10,"description":10,"armGroupLabels":16,"otherNames":17},"DRUG",[9],[9],[19],{"name":20,"affiliation":21,"role":22},"Joyce H Yamamoto, MD","University of Sao Paulo School of Medicine Ophthalmology","PRINCIPAL_INVESTIGATOR",[24],{"name":20,"role":25,"phone":26,"phoneExt":27,"email":28},"CONTACT","55-11-99266-6474",null,"joycehy@uol.com.br",[30],{"facility":31,"status":32,"city":33,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Hospital das Clinicas HCFMUSP, Faculdade de Medicina Universidade de Sao Paulo","RECRUITING","São Paulo","05403-000","Brazil","BR",{"type":38,"coordinates":39},"Point",[40,41],-46.63611,-23.5475,{"lat":41,"lon":40},[44,47],{"name":45,"role":25,"phone":46,"phoneExt":27,"email":28},"Joyce Yamamoto, MD","11992666474",{"name":48,"role":25,"phone":27,"phoneExt":27,"email":49},"Marcelo M Lavezzo, MD","mmlavezzo@gmail.com",{"type":22,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"Joyce Hisae Yamamoto","Professor",[54],{"name":55,"class":56},"Fundação de Amparo à Pesquisa do Estado de São Paulo","OTHER_GOV","100316407",false,"NCT03399175","Early Immunosuppressive Therapy on the Course of Vogt-Koyanagi-Harada Disease","Influência de imunomodulação Precoce Influence of Early Immunosuppressive Therapy on the Course of Vogt-Koyanagi-Harada Disease: a Prospective Study","Inclusion criteria:\n\n\\- acute Vogt-Koyanagi-Harada disease\n\nExclusion criteria:\n\n* non collaborative patient\n* minimum one-year follow-up","ALL","10 Years","70 Years",{"count":67,"type":68},40,"ESTIMATED","INTERVENTIONAL",[71],"NA","This prospective study will include patients with Vogt-Koyanagi-Harada disease from disease onset, treated with early systemic high-dose corticosteroid and immunosuppressive therapy. Clinical and subclinical signs of disease activity added with electroretinogram exams, through predefined intervals, will be evaluated through a minimum 12-month follow-up.",[74],"Vogt Koyanagi Harada Disease",[76,77,78,79,80],"Vogt-Koyanagi-Harada disease","Immunosuppressive therapy","Indocyanine green angiography","Enhanced depth imaging optical coherence tomography","Electroretinogram","2026-05-01",{"date":83,"type":84},"2026-05-07","ACTUAL",{"date":86,"type":84},"2015-03-23",{"date":88,"type":68},"2028-12",{"name":5,"class":6},1]