Oral Intradialytic Amino Acid Supplementation to Vitalize End-stage Kidney Disease Patients on Hemodialysis

Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-64
SponsorThe University of Texas Health Science Center at San Antonio

About this trial

The study will test and compare the efficacy of a single essential amino acid valine with a combination of essential amino acids (EAA) supplement on fatigue, frailty, and cognitive function in end-stage kidney disease (ESKD) patients undergoing hemodialysis (HD) treatment.

Eligibility criteria

Qualifiers

Male or Female

Age 18-64 years

Receiving 3 x weekly in clinic hemodialysis for at least 6 months

Disqualifiers

Hypersensitivity to amino acid(s) and/or any excipient

Clinical documentation of COVID-19

Concomitant intake of amino acids supplements

Current use or abuse of alcohol, marijuana, narcotic, or other substances

Trial design

Treatments tested in this trial

  • Valine
  • EEA

Treatment groups

28 Participants
are divided into 2 treatment groups

Sponsors and collaborators

The University of Texas Health Science Center at San Antonio

Lead sponsor

National Center for Advancing Translational Sciences (NCATS)

Collaborator

IIMS-UT Health San Antonio

Collaborator