[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100053670":3},{"organization":4,"outcomesModule":7,"designInfo":32,"detailedDescription":44,"studyPopulation":35,"armGroups":45,"interventions":58,"overallOfficials":35,"centralContacts":67,"locations":73,"responsibleParty":90,"collaborators":35,"id":94,"slug":35,"hasResults":95,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":35,"eligibilityCriteria":99,"healthyVolunteers":100,"sex":101,"minAge":102,"maxAge":35,"enrollmentInfo":103,"targetDuration":35,"studyType":106,"phases":107,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":76,"whyStopped":35,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":127},{"fullName":5,"class":6},"University of Pecs","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":27},[9],{"measure":10,"description":11,"timeFrame":12},"No-flow time","Time without chest compressions measured from entry into the simulation (collapse recognition) until termination of the scenario (giving the third shock).","During procedure.",[14,17,21,24],{"measure":15,"description":16,"timeFrame":12},"Time to first chest compression","The time (in seconds) until the first chest compression (measured from entering the scenario).",{"measure":18,"description":19,"timeFrame":20},"Time to first shock","The time to the first shock by the AED (in seconds, from the time of entering the scenario).","During procedure",{"measure":22,"description":23,"timeFrame":12},"Chest compression fraction","Proportion of time during which chest compressions are performed (until giving the third shock), calculated from the first chest compression until scenario termination.",{"measure":25,"description":26,"timeFrame":20},"Peri-shock pause","The time without chest compression (in seconds) before and after giving the shock.",[28],{"measure":29,"description":30,"timeFrame":31},"Attitude about T-CPR instructions","Subjective feelings after performing cardiopulmonary resuscitation based on a short survey using Likert-scale based queries (1-4 points, lower numbers indicate worse, higher score indicates better opinion).","Immediately after the CPR procedure (within 15 minutes)",{"allocation":33,"interventionModel":34,"interventionModelDescription":35,"primaryPurpose":36,"observationalModel":35,"timePerspective":35,"maskingInfo":37},"RANDOMIZED","PARALLEL",null,"TREATMENT",{"masking":38,"maskingDescription":39,"whoMasked":40},"TRIPLE","Participants will be informed about their group assignment post-randomization but will be blinded to the study's aims. The dispatcher will be briefed on their specific tasks but will remain blinded to the study hypotheses and outcomes.",[41,42,43],"PARTICIPANT","INVESTIGATOR","OUTCOMES_ASSESSOR","Out-of-hospital cardiac arrest (OHCA) is a major public health problem associated with low survival rates despite advances in emergency care systems. Survival is critically dependent on early recognition, immediate initiation of high-quality chest compressions, and timely defibrillation. Bystander intervention plays a pivotal role in this process, and telephone-assisted cardiopulmonary resuscitation (T-CPR) has been demonstrated to substantially increase the likelihood of CPR initiation prior to the arrival of emergency medical services.\n\nThe increasing availability of automated external defibrillators (AEDs) in public spaces has further strengthened the chain of survival. Early defibrillation is a key determinant of favorable outcomes, particularly in shockable rhythms. However, the integration of AED use into dispatcher-assisted scenarios - especially when only a single rescuer is present - poses practical challenges. In such situations, the rescuer must balance multiple tasks, including chest compressions, AED retrieval, device preparation, and adherence to voice prompts, all of which may introduce interruptions in compressions and increase no-flow time.\n\nWhile the benefits of T-CPR and AED use independently are well established, there is limited evidence on how dispatcher instructions can optimally coordinate these interventions in single-rescuer scenarios. In particular, it remains unclear whether modified, AED-optimized T-CPR instructions can reduce no-flow time and improve chest compression fraction (CCF) by minimizing unnecessary interruptions and optimizing task sequencing.\n\nThis prospective, randomized, controlled simulation study aims to evaluate the effect of modified telephone cardiopulmonary resuscitation (T-CPR) instructions optimized for automated external defibrillator (AED) use on no-flow time and chest compression fraction (CCF) during single-rescuer resuscitation. Participants are randomized to receive either standard T-CPR instructions or enhanced instructions focusing on minimizing interruptions in chest compressions and reducing time to first compression during AED use.",[46,52],{"label":47,"type":48,"description":49,"interventionNames":50},"Standard T-CPR","EXPERIMENTAL","Participants perform dispatcher-assisted CPR based on the European Resuscitation Council (ERC) 2025 guidelines and the national standard DA-CPR protocol.",[51],"Behavioral: T-CPR",{"label":53,"type":54,"description":55,"interventionNames":56},"AED-optimized T-CPR","ACTIVE_COMPARATOR","Participants perform dispatcher-assisted CPR based on the European Resuscitation Council (ERC) 2025 guidelines and a modified national DA-CPR protocol.",[57],"Behavioral: AED-optimized T-CPR",[59,64],{"type":60,"name":61,"description":62,"armGroupLabels":63,"otherNames":35},"BEHAVIORAL","T-CPR","Participants receive structured telephone CPR instructions reflecting current national practice. AED retrieval is instructed early; however, no additional guidance is provided to optimize timing or minimize interruptions during AED use.",[47],{"type":60,"name":53,"description":65,"armGroupLabels":66,"otherNames":35},"Participants receive standard T-CPR instructions supplemented with specific guidance aimed at:\n\n* minimizing interruptions in chest compressions,\n* reducing time to first chest compression,\n* optimizing AED use workflow.\n\nKey elements include:\n\n* immediate activation of the AED upon retrieval,\n* initiation of chest compressions even if AED voice prompts have not yet reached relevant steps,\n* continuation of compressions during AED preparation and charging (when appropriate),\n* minimization of pauses before and after shock delivery.",[53],[68],{"name":69,"role":70,"phone":71,"phoneExt":35,"email":72},"Bálint Bánfai, Ph.D.","CONTACT","+3630501500","balint.banfai@etk.pte.hu",[74],{"facility":75,"status":76,"city":77,"state":35,"zip":78,"country":79,"countryCode":80,"cosmosGeoPoint":81,"geoPoint":86,"contacts":87},"University of Pécs","RECRUITING","Pécs","7621","Hungary","HU",{"type":82,"coordinates":83},"Point",[84,85],18.22814,46.07617,{"lat":85,"lon":84},[88],{"name":69,"role":70,"phone":89,"phoneExt":35,"email":72},"+3672501500",{"type":91,"investigatorFullName":92,"investigatorTitle":93,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"PRINCIPAL_INVESTIGATOR","Dr. Bálint Bánfai","associate professor","100053670",false,"NCT07520877","Effect of AED-optimized Telephone-assisted CPR Instructions on No-flow Time and Chest Compression Fraction","Effect of AED-optimized Telephone-assisted CPR Instructions on No-flow Time and Chest Compression Fraction in a Single-rescuer Cardiac Arrest Scenario - a Randomized-controlled Simulation Study","Inclusion Criteria:\n\n* Adolescents and adults (≥16 years)\n* Healthcare professionals or laypersons\n* Voluntary participation\n\nExclusion Criteria:\n\n* pregnant women\n* people with cardio-pulmonary and musculoskeletal diseases or any other impairment that would risk harm for the volunteer while performing CPR\n* physical and\u002For psychological disabilities\n* technical issue during data collection",true,"ALL","16 Years",{"count":104,"type":105},80,"ESTIMATED","INTERVENTIONAL",[108],"NA","Out-of-hospital cardiac arrest (OHCA) remains a leading cause of mortality worldwide, with survival highly dependent on the immediate initiation of bystander cardiopulmonary resuscitation (CPR). Early recognition, prompt chest compressions, and rapid defibrillation are critical components of the chain of survival. Telephone-assisted CPR (T-CPR) provided by emergency dispatchers has been shown to significantly increase bystander intervention rates and improve outcomes. While the availability and use of automated external defibrillators (AEDs) further enhance survival, the optimal integration of AED use into dispatcher-guided, single-rescuer scenarios remains insufficiently studied.\n\nThis prospective, randomized, controlled simulation study aims to evaluate the effect of modified telephone cardiopulmonary resuscitation (T-CPR) instructions optimized for automated external defibrillator (AED) use on no-flow time and chest compression fraction (CCF) during single-rescuer resuscitation. Participants are randomized to receive either standard T-CPR instructions or enhanced instructions focusing on minimizing interruptions in chest compressions and reducing time to first compression during AED use.",[111],"Cardiac Arrest (CA)",[113,114,115,116,117],"cardiac arrest","automated external defibrillator","dispatcher-assisted cardiopulmonary resuscitation","no-flow time","chest compression fraction","2026-07-09",{"date":120,"type":121},"2026-07-13","ACTUAL",{"date":123,"type":121},"2026-07-10",{"date":125,"type":105},"2026-09-30",{"name":5,"class":6},1]