Effect of AED-optimized Telephone-assisted CPR Instructions on No-flow Time and Chest Compression Fraction

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age16+
SponsorUniversity of Pecs

About this trial

Out-of-hospital cardiac arrest (OHCA) remains a leading cause of mortality worldwide, with survival highly dependent on the immediate initiation of bystander cardiopulmonary resuscitation (CPR). Early recognition, prompt chest compressions, and rapid defibrillation are critical components of the chain of survival. Telephone-assisted CPR (T-CPR) provided by emergency dispatchers has been shown to significantly increase bystander intervention rates and improve outcomes. While the availability and use of automated external defibrillators (AEDs) further enhance survival, the optimal integration of AED use into dispatcher-guided, single-rescuer scenarios remains insufficiently studied.

This prospective, randomized, controlled simulation study aims to evaluate the effect of modified telephone cardiopulmonary resuscitation (T-CPR) instructions optimized for automated external defibrillator (AED) use on no-flow time and chest compression fraction (CCF) during single-rescuer resuscitation. Participants are randomized to receive either standard T-CPR instructions or enhanced instructions focusing on minimizing interruptions in chest compressions and reducing time to first compression during AED use.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adolescents and adults (≥16 years)

Healthcare professionals or laypersons

Voluntary participation

Disqualifiers

pregnant women

people with cardio-pulmonary and musculoskeletal diseases or any other impairment that would risk harm for the volunteer while performing CPR

physical and/or psychological disabilities

technical issue during data collection

Trial design

Design model

Parallel

Treatments tested in this trial

  • T-CPR

    Behavioral

    Participants receive structured telephone CPR instructions reflecting current national practice. AED retrieval is instructed early; however, no additional guidance is provided to optimize timing or minimize interruptions during AED use.

  • AED-optimized T-CPR

    Behavioral

    Participants receive standard T-CPR instructions supplemented with specific guidance aimed at: * minimizing interruptions in chest compressions, * reducing time to first chest compression, * optimizing AED use workflow. Key elements include: * immediate activation of the AED upon retrieval, * initiation of chest compressions even if AED voice prompts have not yet reached relevant steps, * continuation of compressions during AED preparation and charging (when appropriate), * minimization of pauses before and after shock delivery.

Treatment groups

80 Participants
are divided into 2 treatment groups
Group A: Standard T-CPRExperimental treatment 1 intervention
Group B: AED-optimized T-CPRActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

No-flow time

Time without chest compressions measured from entry into the simulation (collapse recognition) until termination of the scenario (giving the third shock).

Time frame
During procedure.

Secondary outcomes

1

Time to first chest compression

The time (in seconds) until the first chest compression (measured from entering the scenario).

Time frame
During procedure.
2

Time to first shock

The time to the first shock by the AED (in seconds, from the time of entering the scenario).

Time frame
During procedure
3

Chest compression fraction

Proportion of time during which chest compressions are performed (until giving the third shock), calculated from the first chest compression until scenario termination.

Time frame
During procedure.
4

Peri-shock pause

The time without chest compression (in seconds) before and after giving the shock.

Time frame
During procedure

Other outcomes

1

Attitude about T-CPR instructions

Subjective feelings after performing cardiopulmonary resuscitation based on a short survey using Likert-scale based queries (1-4 points, lower numbers indicate worse, higher score indicates better opinion).

Time frame
Immediately after the CPR procedure (within 15 minutes)

Sponsors and contacts

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