Effect of Isometric Handgrip Exercise on Blood Pressure in Pregnant Women

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorUniversity of Poitiers

About this trial

Hypertension during pregnancy is a major public health concern, increasing the risk of cardiovascular complications for both the mother and the fetus. Women with chronic hypertension are at higher risk of adverse outcomes, and elevated blood pressure during pregnancy has also been associated with long-term cardiovascular and cognitive impairments.Regular physical activity is recognized as an effective non-pharmacological strategy to reduce blood pressure. Among different exercise modalities, isometric exercise has shown promising effects in lowering blood pressure in the general population, with minimal cardiovascular strain. However, its effects and safety in pregnant women, particularly those with hypertension, remain poorly understood.In addition to cardiovascular alterations, hypertension during pregnancy may also impact cognitive function, potentially through changes in cerebral perfusion and vascular function. Despite these associations, the combined cardiovascular and cognitive responses to exercise in this population have not been fully explored.This study aims to investigate the effects of isometric handgrip exercise on cardiovascular and cognitive responses in pregnant women with and without chronic hypertension, in order to better understand its potential as a safe and effective non-pharmacological intervention during pregnancy.

Eligibility criteria

Qualifiers

Pregnant women covered by the French National Health Insurance system

Pregnant women who do not object to participation in the study

Women with chronic hypertension present before pregnancy (diagnosed within the past 5 years), defined as systolic blood pressure (SBP) ≥ 140 mmHg or diastolic blood pressure (DBP) ≥ 90 mmHg, without antihypertensive treatment

Normotensive pregnant women, defined as systolic blood pressure (SBP) < 140 mmHg and diastolic blood pressure (DBP) < 90 mmHg before pregnancy

Disqualifiers

Current treatment for chronic or gestational hypertension

Known cardiovascular disease other than chronic hypertension

Age under 18 years

Persons deprived of liberty

Trial design

Treatments tested in this trial

  • Isometric Handgrip Exercise
  • Control Rest

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Poitiers

Lead sponsor

Poitiers University Hospital

Collaborator

Laboratory MOVE, Faculty of Sport Sciences, University of Poitiers, France

Collaborator