About this trial
Hypertension during pregnancy is a major public health concern, increasing the risk of cardiovascular complications for both the mother and the fetus. Women with chronic hypertension are at higher risk of adverse outcomes, and elevated blood pressure during pregnancy has also been associated with long-term cardiovascular and cognitive impairments.Regular physical activity is recognized as an effective non-pharmacological strategy to reduce blood pressure. Among different exercise modalities, isometric exercise has shown promising effects in lowering blood pressure in the general population, with minimal cardiovascular strain. However, its effects and safety in pregnant women, particularly those with hypertension, remain poorly understood.In addition to cardiovascular alterations, hypertension during pregnancy may also impact cognitive function, potentially through changes in cerebral perfusion and vascular function. Despite these associations, the combined cardiovascular and cognitive responses to exercise in this population have not been fully explored.This study aims to investigate the effects of isometric handgrip exercise on cardiovascular and cognitive responses in pregnant women with and without chronic hypertension, in order to better understand its potential as a safe and effective non-pharmacological intervention during pregnancy.
Eligibility criteria
Qualifiers
Pregnant women covered by the French National Health Insurance system
Pregnant women who do not object to participation in the study
Women with chronic hypertension present before pregnancy (diagnosed within the past 5 years), defined as systolic blood pressure (SBP) ≥ 140 mmHg or diastolic blood pressure (DBP) ≥ 90 mmHg, without antihypertensive treatment
Normotensive pregnant women, defined as systolic blood pressure (SBP) < 140 mmHg and diastolic blood pressure (DBP) < 90 mmHg before pregnancy
Disqualifiers
Current treatment for chronic or gestational hypertension
Known cardiovascular disease other than chronic hypertension
Age under 18 years
Persons deprived of liberty
Trial design
Treatments tested in this trial
- Isometric Handgrip Exercise
- Control Rest
Treatment groups
Sponsors and collaborators
University of Poitiers
Lead sponsor
Poitiers University Hospital
Collaborator
Laboratory MOVE, Faculty of Sport Sciences, University of Poitiers, France
Collaborator