[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603931":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":52,"collaborators":25,"id":56,"slug":25,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":25,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":77,"whyStopped":25,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Zhongshan Ophthalmic Center, Sun Yat-sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group","EXPERIMENTAL","The eye with higher hyperopia will be fitted with light-blocking lenses for full-time wear, while the fellow eye with lower hyperopia will be fitted with conventional single-vision lenses for full-time wear, over 12 months. Follow-up visits will be scheduled at 6 months (±15 days) and 12 months (±15 days) after lens fitting. Lens replacement will be arranged if a refractive change greater than 0.50 diopters occurs or if the lenses become severely damaged",[13],"Other: light-blocking lenses",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","PLACEBO_COMPARATOR","Both eyes of the subjects will be fitted with conventional single-vision lenses for full-time wear over 12-months. Follow-up visits will be scheduled at 6 months (±15 days) and 12 months (±15 days) after lens fitting. Lens replacement will be arranged if a refractive change greater than 0.50 diopters is detected or if the lenses become severely damaged.",[19],"Other: single-vision lenses",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"light-blocking lenses","The eye with higher hyperopia will be fitted with light-blocking lenses for full-time wear, while the fellow eye with lower hyperopia will be fitted with conventional single-vision lenses for full-time wear, over 12 months",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"single-vision lenses","Both eyes of the subjects will be fitted with conventional single-vision lenses for full-time wear over 12 months.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Jinrong Li, MD PhD","CONTACT","86-020-87330351","lijingr3@mail.sysu.edu.cn",[37],{"facility":38,"status":25,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Zhongshan Ophthalmic Center","Guangzhou","Guangdong","510060","China","CN",{"type":45,"coordinates":46},"Point",[47,48],113.25,23.11667,{"lat":48,"lon":47},[51],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Jingrong Li","Professor","100603931",false,"NCT07142928","Effect of Light-Blocking Lenses on Hyperopic Anisometropic Children","A Prospective Randomized Controlled Trial on the Effect of Light-Blocking Lenses on Emmetropization in Hyperopic Anisometropic Children","Inclusion Criteria:\n\n* Aged 6 years or older and 12 years or younger;\n* The more hyperopic eye has a spherical refractive error between +3.0 D and +7.5 D; the less hyperopic eye has a spherical refractive error of at least +2.0 D; cylindrical refractive error between -2.0 D and 0 D; interocular difference in spherical power \\>=1.5 D and in cylindrical power \\\u003C=1.0 D;\n* Best-corrected visual acuity of 0.0 logMAR or better in both eyes;\n* Ocular deviation with spectacles less than 10 prism diopters;\n* Has been wearing standard single-vision spectacles regularly for more than six months;\n* In good general health, capable of receiving the study intervention, and willing to comply with the study protocol;\n* Written informed consent obtained from both the parent\u002Fguardian and the child, with agreement to comply with all study procedures and maintain follow-up availability throughout the study period;\n\nExclusion Criteria:\n\n* History of ocular trauma or eye surgery;\n* Presence of pathological abnormalities on anterior or posterior segment examination, or a history of organic ocular diseases such as cataract, glaucoma, corneal disease, or fundus disorders;\n* Intraocular pressure greater than 21 mmHg;\n* Presence of systemic diseases or other conditions deemed unsuitable for study participation;\n* Any other condition deemed inappropriate for participation in the clinical trial by the investigator;","ALL","6 Years","12 Years",{"count":66,"type":67},90,"ESTIMATED","INTERVENTIONAL",[70],"NA","To evaluate the effectiveness of light-blocking lenses in promoting emmetropization and reducing anisometropia in children with hyperopic anisometropia, and to assess the impact of light-intercepting lenses on visual function in this population.",[73,74],"Anisometropia","Hyperopia",[73,74,22,76],"emmetropization","NOT_YET_RECRUITING","2025-08-25",{"date":80,"type":81},"2025-08-27","ACTUAL",{"date":78,"type":67},{"date":84,"type":67},"2027-06-30",{"name":5,"class":6},1]