[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631355":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":32,"locations":42,"responsibleParty":59,"collaborators":26,"id":63,"slug":26,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":26,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":26,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":45,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Inonu University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group","ACTIVE_COMPARATOR","Patients in this group receive scaling and root planing (SRP) only.",[13],"Procedure: Scaling and Root Planing",{"label":15,"type":16,"description":17,"interventionNames":18},"Test Group","EXPERIMENTAL","Patients in this group receive scaling and root planing (SRP) followed by the use of Morus nigra mouthwash twice daily for 14 days",[13,19],"Dietary Supplement: Morus Nigra Mouthwash",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Scaling and Root Planing","Mechanical removal of dental plaque and calculus from the tooth surfaces",[9,15],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"DIETARY_SUPPLEMENT","Morus Nigra Mouthwash","Morus nigra extract based mouthwash, used 2 times a day for 14 days",[15],[33,38],{"name":34,"role":35,"phone":36,"phoneExt":26,"email":37},"Omer Alperen Kırmızıgul, Assistant Professor","CONTACT","+905073951987","alperen.kirmizigul@inonu.edu.tr",{"name":39,"role":35,"phone":40,"phoneExt":26,"email":41},"Burak Koçak, Dds","+9005446609444","kocakburak44@gmail.com",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":26,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Inonu University Faculty of Dentistry","RECRUITING","Battalgazi","Malatya","44300","Turkey (Türkiye)",{"type":51,"coordinates":52},"Point",[53,54],38.3585,38.42286,{"lat":54,"lon":53},[57],{"name":58,"role":35,"phone":36,"phoneExt":26,"email":37},"Omer Alperen Kırmızıgul",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Ömer Alperen Kırmızıgül","Assistant Professor","100631355",false,"NCT07499596","Effect of Morus Nigra Mouthwash on Gingivitis Treatment","Evaluation of the Efficacy of Morus Nigra Mouthwash as an Adjunct to Scaling and Root Planing in the Treatment of Gingivitis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of generalized gingivitis (Gingival Index \\> 1).\n* Presence of at least 20 natural teeth.\n* Systemically healthy individuals.\n* Ability to provide informed consent.\n\nExclusion Criteria:\n\n* Smoking or use of tobacco products.\n* Presence of periodontitis (no clinical attachment loss).\n* Use of antibiotics or anti-inflammatory drugs in the last 6 months.\n* Pregnancy or lactation.\n* History of allergy to Morus nigra or mouthwash components.\n* Systemic diseases (Diabetes, cardiovascular diseases, etc.).","ALL","18 Years","65 Years",{"count":73,"type":74},30,"ESTIMATED","INTERVENTIONAL",[77],"NA","The aim of this study is to evaluate the clinical, microbiological, and biochemical effects of Morus nigra (black mulberry) mouthwash when used as an adjunct to non-surgical periodontal treatment (scaling and root planing - SRP) in patients with generalized gingivitis. Participants will be randomly assigned to two groups: one receiving SRP only, and the other receiving SRP plus Morus nigra mouthwash twice daily for 14 days. Clinical parameters, cytokine levels in gingival crevicular fluid (TNF-alpha, IL-1beta, IL-10), and subgingival bacterial load will be assessed at baseline, 1 month, and 3 months.",[80],"Gingivitis",[82,83,84],"Morus nigra","Mouthwash","Cytokines","2026-04-08",{"date":87,"type":88},"2026-04-13","ACTUAL",{"date":90,"type":88},"2026-01-15",{"date":92,"type":74},"2026-07-15",{"name":5,"class":6},1]