[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100522431":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":11,"centralContacts":27,"locations":33,"responsibleParty":49,"collaborators":11,"id":51,"slug":11,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":11,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":11,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":72,"overallStatus":35,"whyStopped":11,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Xijing Hospital","OTHER",[8,12,18],{"label":9,"type":10,"description":11,"interventionNames":11},"Preoperative","NO_INTERVENTION",null,{"label":13,"type":14,"description":15,"interventionNames":16},"postoperative (6 weeks)","EXPERIMENTAL","The patients were injected with PRP.",[17],"Drug: Sodium hyaluronate injection",{"label":19,"type":14,"description":15,"interventionNames":20},"postoperative (3 months)",[17],[22],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":11},"DRUG","Sodium hyaluronate injection","The control group was injected into the joint cavity with sodium hyaluronate injection..",[19,13],[28],{"name":29,"role":30,"phone":31,"phoneExt":11,"email":32},"Yanyan Jia","CONTACT","+862984771794","xiyyllwyh@163.com",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Xi'an","Shannxi","710034","China","CN",{"type":42,"coordinates":43},"Point",[44,45],108.92861,34.25833,{"lat":45,"lon":44},[48],{"name":29,"role":30,"phone":31,"phoneExt":11,"email":32},{"type":50,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100522431",false,"NCT06082531","Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis","Therapeutic Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis and Periarticular Tissue Injury","Inclusion Criteria:\n\n* The age range of the participants was 20 to 60 years old. Through a comprehensive clinical and imaging examination, it was conclusively determined that the individuals had knee osteoarthritis or experienced injuries to the cart, and meniscus surrounding the knee joint.\n* The preoperative routine tests and examinations revealed no contraindications.\n* Revised sentence: \"Informed consent of the patient\n\nExclusion Criteria:\n\n* The platelet count or function exhibits significant abnormalities、Systemic infection transmitted through the bloodstream.\n* Prolonged usage of anti-inflammatory drugs and systemic corticoid administration.\n* In injection site or damage to the skin.\n* Patients with tumors or undergoing radiotherapy and chemotherapy.\n* Pregnant or breastfeeding women.\n* Individuals with mental illnesses who are unable to cooperate with follow-up procedures.\n* Contraindications for MRI、Patients or their families do consent to participate in the study.\n* Other circumstances that render participation in the study unsuitable.","ALL","20 Years","60 Years",{"count":61,"type":62},300,"ESTIMATED","INTERVENTIONAL",[65],"NA","To evaluate the safety and effectiveness of PRP injection therapy in the repair of osteoarthritis and periarticular soft tissue injury through a single-center, exploratory clinical study, and to provide a more reliable basis for the treatment of joint injury.",[68,69,70,71],"Platelets-rich Plasma","Osteoarthritis Knees Both","Meniscus Disorder","Cartilage Injury",[73,74,71,75],"platelets-rich plasma","Osteoarthritis","Meniscus Injury","2025-04-06",{"date":78,"type":79},"2025-04-09","ACTUAL",{"date":81,"type":79},"2023-09-01",{"date":83,"type":62},"2025-12-31",{"name":5,"class":6},1]