[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619692":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":10,"locations":26,"responsibleParty":45,"collaborators":10,"id":49,"slug":10,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":10,"eligibilityCriteria":54,"healthyVolunteers":50,"sex":55,"minAge":56,"maxAge":10,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Future University in Egypt","OTHER",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"Prehospital ARNI users",null,[12],"Other: Prehospital ARNI use",{"label":14,"type":10,"description":10,"interventionNames":15},"Non-Prehospital ARNI users",[16],"Other: No prehospital ARNI use",[18,22],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"Prehospital ARNI use","Participants who were using ARNI therapy before hospital admission",[9],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"No prehospital ARNI use","Participants who were not using ARNI therapy before hospital admission",[14],[27],{"facility":28,"status":29,"city":30,"state":10,"zip":10,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Mansoura university Hospital","RECRUITING","Al Mansurah","Egypt","EG",{"type":34,"coordinates":35},"Point",[36,37],31.38069,31.03637,{"lat":37,"lon":36},[40],{"name":41,"role":42,"phone":43,"phoneExt":10,"email":44},"Mansoura University Hospital","CONTACT","+201020296516","Hanaa.mm.abdelaziz@mans.edu.eg",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mrwan Ayman Ahmed Eassa","MS Student, Clinical Pharmacy Department, Future University in Egypt","100619692",false,"NCT07347925","Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF","Evaluating the Impact of Pre-Hospital Angiotensin Receptor-Neprilysin Inhibitor (ARNI) Therapy on Short-Term Clinical Outcomes in Heart Failure Patients With Reduced Ejection Fraction: A Comparative Study","Inclusion Criteria:\n\n* \\>= 18 years, male or female EF \\\u003C40%\n\nExclusion Criteria:\n\n* EF\\>40% Pregnancy or breastfeeding","ALL","18 Years",{"count":58,"type":59},140,"ESTIMATED","OBSERVATIONAL","This study looks at people with heart failure who are admitted to the hospital. The goal of the study is to understand whether taking a heart failure medicine called angiotensin receptor-neprilysin inhibitor (ARNI) before hospital admission affects short-term health outcomes.\n\nThe study will compare two groups of participants: those who were already taking ARNI before coming to the hospital and those who were not. Information will be collected from medical records during the hospital stay, including heart-related events, kidney-related events, and how long participants stay in the hospital.\n\nSome participants will also be followed for a short period after discharge. This study may help improve understanding of outcomes associated with ARNI use in people with heart failure in routine clinical care.",[63],"Heart Failure",[63,65,66,67],"NYHA class","Sacubitril\u002FValsartan","Chronic kidney disease","2026-01-11",{"date":70,"type":71},"2026-01-16","ACTUAL",{"date":73,"type":59},"2026-01-10",{"date":75,"type":59},"2026-05-01",{"name":5,"class":6},1]