Health TrialsbyHealthPanel

Effect of Rectus Block Timing on Opioid Use

ConditionsProstate CancerPain ManagementNociception Level Index(NoL)Nociception MonitoringOpioid Consumption
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18+
SponsorKoc University Hospital

About this trial

The aim of this study is to observe the effect of administering local anesthetic to the abdominal wall at the beginning or end of surgery under general anesthesia on opioid consumption during surgery. The hypothesis of this study is to demonstrate that administering a rectus sheath block before the surgical procedure under general anesthesia is effective in reducing intraoperative opioid consumption and opioid-related side effects compared to administering it after the surgery is completed.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

<18 years of age

ASA (American Society of Anesthesiologists) IV, V patients

Non-elective emergency cases

Previous major abdominal/pelvic surgery

Trial design

Design model

Parallel

Treatments tested in this trial

  • Early bilateral rectus sheat block

    Procedure/Surgery

    Bilateral rectus sheat block will be performed after the anesthesia induction, before the start of the surgery

  • Late bilateral rectus sheat block

    Procedure/Surgery

    Bilateral rectus sheat block will be performed after the completion of the surgery, before the end of general anesthesia

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: Preoperative RSB GroupActive comparator 1 intervention
Group B: Postoperative RSB GroupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Total intraoperatif remifentanil consumption

Time frame
Total operative duration
2

Average intraoperative remifentanil consumption

Total intraoperative remifentail consumption divided by the weight of the patient (kg) and total operative duration (minutes). (mcg/kg/dk)

Time frame
Total operative duration

Secondary outcomes

1

Cumulative opioid consumption at postoperative 1st hour

Cumulative opioid consumption at postoperative 1st hour in IV morphine equivalent

Time frame
From the end of the surgery to the end of the first postoperative hour
2

Cumulative opioid consumption at postoperative 6th hour

Cumulative opioid consumption at postoperative 6th hour in IV morphine equivalent

Time frame
From the end of the surgery to the end of the 6th postoperative hour
3

Cumulative opioid consumption at postoperative 12th hour

Cumulative opioid consumption at postoperative 12th hour in IV morphine equivalent

Time frame
From the end of the surgery to the end of the 12th postoperative hour
4

Cumulative opioid consumption at postoperative 24th hour

Cumulative opioid consumption at postoperative 24th hour in IV morphine equivalent

Time frame
From the end of the surgery to the end of the 24th postoperative hour

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Koc University Hospital

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: