[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627742":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":40,"collaborators":26,"id":44,"slug":26,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":26,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":67,"whyStopped":26,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":26},{"fullName":5,"class":6},"Sohag University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group","EXPERIMENTAL","treatment of microbial keratitis by antibiotic with sodium chloride 5%",[13,14],"Drug: Sodium chloride 5% solution","Drug: quinolones",{"label":16,"type":17,"description":18,"interventionNames":19},"Control group","ACTIVE_COMPARATOR","Treatment of microbial keratitis by antibiotics only",[14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Sodium chloride 5% solution","Use Sodium chloride 5% solution with usual anti microbial drugs",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"quinolones","Use of usual topical anti microbial treatment only",[16,9],[32,37],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Nancy Safwat Kaldas, Specialist","CONTACT","01200933440","nansy_safwat_post@med.sohag.edu.eg",{"name":38,"role":34,"phone":39,"phoneExt":26,"email":26},"Amr Mounir Mohamed, Assistant professor","01005026170",{"type":41,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Nancy Safwat Kaldes","Principal Investigator","100627742",false,"NCT07452588","Effect of Sodium Chloride 5% Solution as an Adjuvant Treatment With Antimicrobial Therapy in the Treatment of Bacterial Infectious Keratitis","keratitis","IncluInclusion Criteria\n\n* Age ≥ 18 years.\n* Clinically diagnosed bacterial infectious keratitis\n* Positive corneal scraping or strong clinical suspicion of bacterial cause.\n* Ability to provide informed consent and attend follow-up visits\n\nExclusion Criteria:\n\n* • Fungal, viral, or acanthamoeba keratitis.\n\n  * Recent (\\\u003C7 days) topical corticosteroid use.\n  * Corneal perforation or impending perforation.\n  * History of hypersensitivity to study agents.\n  * Systemic immunocompromised state (uncontrolled diabetes, Human immune defecinicy virus).\n  * Poor compliance expected with follow-up.","ALL","18 Years","60 Years",{"count":54,"type":55},40,"ESTIMATED","INTERVENTIONAL",[58],"NA","This study aims to detect the effect of sodium chloride 5% solution as an adjuvant treatment with antimicrobial therapy in treatment of bacterial infectious keratits and to assess whether NaCl 5% accelerates epithelial healing, improves microbial eradication, and enhances visual outcomes in bacterial infectious keratitis.",[61,62,63],"Infectious Keratitis","Adjuvant Treatment Bacterial Infectious Keratitis","Sodium Chloride 5% Solution",[65,66],"Bacterial infectious keratitis","Sodiunchloride5%","NOT_YET_RECRUITING","2026-03-02",{"date":70,"type":71},"2026-03-05","ACTUAL",{"date":73,"type":55},"2026-02",{"date":75,"type":55},"2027-02",{"name":5,"class":6}]