[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100412463":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":29,"responsibleParty":66,"collaborators":68,"id":77,"slug":25,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":25,"eligibilityCriteria":82,"healthyVolunteers":78,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":25,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":25,"overallStatus":32,"whyStopped":25,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"The University of Hong Kong","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Vitamin D","ACTIVE_COMPARATOR","Vitamin D 50,000 IU\u002F week for 4 weeks, followed by 50,000 IU once every 2 weeks for 52 weeks Those who remain anovulatory after 6 months will be treated with a 6-month course of letrozole (2.5mg to 7.5mg for 5 days per cycle titrated according to response) for ovulation induction.",[13],"Dietary Supplement: Vitamin D",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Placebo tablets with same external appearance for 52 weeks Those who remain anovulatory after 6 months will be treated with a 6-month course of letrozole (2.5mg to 7.5mg for 5 days per cycle titrated according to response) for ovulation induction.",[19],"Other: Placebo",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Vitamin D supplementation",[9],null,{"type":6,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Placebo tablets with the same external appearance",[15],[30,47,56],{"facility":31,"status":32,"city":33,"state":25,"zip":25,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Kwong Wah Hospital","RECRUITING","Hong Kong","HK",{"type":36,"coordinates":37},"Point",[38,39],114.17469,22.27832,{"lat":39,"lon":38},[42],{"name":43,"role":44,"phone":45,"phoneExt":25,"email":46},"Shui Fan Lai, MBBS, MRCOG","CONTACT","+852 35175183","lsf087@ha.org.hk",{"facility":48,"status":49,"city":33,"state":25,"zip":25,"country":33,"countryCode":34,"cosmosGeoPoint":50,"geoPoint":52,"contacts":53},"Princess Margaret Hospital","NOT_YET_RECRUITING",{"type":36,"coordinates":51},[38,39],{"lat":39,"lon":38},[54],{"name":55,"role":44,"phone":25,"phoneExt":25,"email":25},"Rebecca S.F. Wan, MBBS, MRCOG",{"facility":57,"status":32,"city":33,"state":25,"zip":25,"country":33,"countryCode":34,"cosmosGeoPoint":58,"geoPoint":60,"contacts":61},"Queen Mary Hospital, University of Hong Kong",{"type":36,"coordinates":59},[38,39],{"lat":39,"lon":38},[62],{"name":63,"role":44,"phone":64,"phoneExt":25,"email":65},"Jennifer Ka Yee Ko, MBBS","22554647","jenko@hku.hk",{"type":67,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[69,70,73,75],{"name":31,"class":6},{"name":71,"class":72},"Princess Margaret Hospital, Hong Kong","OTHER_GOV",{"name":74,"class":6},"Pamela Youde Nethersole Eastern Hospital",{"name":76,"class":6},"The Queen Elizabeth Hospital","100412463",false,"NCT04650880","Effect of Vitamin D on Ovulation Rate in Women With Polycystic Ovary Syndrome","A Randomized Double-blind Controlled Trial on the Effect of Vitamin D on Ovulation Rate of Women With Polycystic Ovary Syndrome","Inclusion Criteria:\n\n* Premenopausal\n* Aged 18-40 years\n* Irregular long menstrual cycles (\\>35 days)\n* PCOS according to the Rotterdam criteria\n* Agree for transvaginal ultrasound\n\nExclusion Criteria:\n\n* Use of hormonal medication (including contraception) within 3 months prior to study inclusion, except the use of a progestogen to induce withdrawal bleeding every 3 months\n* History of any medical condition or medications that may predispose to vitamin D sensitivity, altered vitamin D metabolism and\u002F or hypercalcemia, including active tuberculosis or current therapy for tuberculosis, sarcoidosis, history of renal\u002F ureteral stones, parathyroid disease, renal or liver failure or current use of anti-convulsants\n* Use of insulin-sensitizing drugs, lipid lowering drugs or anti-hypertensive\n* Anticipated to use the above medications in the coming one year\n* Known type 2 diabetes mellitus\n* Refusal to join the study\n* Abnormal blood calcium level\n\nFor those on supplements, we asked them to stop their own supplements.","FEMALE","18 Years","40 Years",{"count":87,"type":88},220,"ESTIMATED","INTERVENTIONAL",[91],"NA","This is a randomized double-blind controlled trial on the effect of vitamin D supplementation to assess the ovulation rate of women with polycystic ovary syndrome (PCOS) and other reproductive, endocrine and metabolic outcomes after one year of treatment.",[94,95],"Polycystic Ovary Syndrome","Anovulation","2024-05-13",{"date":98,"type":99},"2024-05-14","ACTUAL",{"date":101,"type":99},"2021-01-26",{"date":103,"type":88},"2026-12-31",{"name":5,"class":6},3]