[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639527":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":34,"collaborators":10,"id":38,"slug":10,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":10,"eligibilityCriteria":43,"healthyVolunteers":39,"sex":44,"minAge":45,"maxAge":10,"enrollmentInfo":46,"targetDuration":49,"studyType":50,"phases":10,"briefSummary":51,"conditions":52,"keywords":10,"overallStatus":21,"whyStopped":10,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":63},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"diaphragmatic and parasternal muscles function assessment",null,"Patients who fulfilling the initial parameters for possibility of weaning will undergo spontaneous breathing trial (SBT) for 30 minutes.\n\nAll patients will be positioned in a semi sitting position at approximately 30 degree, and will be monitored closely during SBT period.\n\nUltrasound assessment for the parasternal intercostal and diaphragmatic muscle functions will be done at the end of SBTs for all patients.\n\nUltrasound assessment of diaphragm:\n\nDiaphragmatic excursion; The diaphragmatic movement will be measured using a 3.5-MHz ultrasound probe. With the probe fixed on the chest wall during respiration, the patient will be asked to take a maximum breath. The right hemi-diaphragm will be measured by positioning the probe between the mid-clavicular and mid-axillary lines below the right costal margin (subcostal approach) using the liver as acoustic window. The probe will be positioned medially, cephalic and dorsally. Till the hemi-diaphragm will be well visualized. The M-mood will be ap",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Mohamed I Ezz eldein","CONTACT","+2-1148394581","mohamedislam@med.asu.edu.eg",[19],{"facility":20,"status":21,"city":22,"state":10,"zip":10,"country":23,"countryCode":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":31},"Ain shams university hospitals","RECRUITING","Cairo","Egypt","EG",{"type":26,"coordinates":27},"Point",[28,29],31.24967,30.06263,{"lat":29,"lon":28},[32],{"name":33,"role":15,"phone":16,"phoneExt":10,"email":17},"Mohamed I Ezz Eldein",{"type":35,"investigatorFullName":36,"investigatorTitle":37,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","mohamed islam ezz el dein amer","Dr","100639527",false,"NCT07630662","Effectiveness of Diaphragmatic Function and Parasternal Intercostal Muscles Functions as Predictors for Successful Weaning From Mechanical Ventilation","Ultrasound Evaluation of Diaphragmatic Functions and Parasternal Intercostal Muscle Thickening Fraction as Predictors of Successful Weaning From Mechanical Ventilation.","Inclusion Criteria:\n\n* 1\\. Adult patients more than 18 years old. 2. Patient on mechanical ventilation more than 48 hours.\n\nExclusion Criteria:\n\n* 1\\. Declining to give a written informed consent. 2. Diaphragmatic paralysis or injury","ALL","18 Years",{"count":47,"type":48},77,"ESTIMATED","2 Days","OBSERVATIONAL","Critically ill patients frequently develop respiratory muscle dysfunction that may contribute to difficult and prolonged weaning from mechanical ventilation. that is besides complications such as barotrauma, ventilator-acquired pneumonia, accumulation of secretions, and lung atelectasis.\n\nThe ultrasound estimation of parasternal intercostal muscle and diaphragmatic functions is a method to evaluate if there is a good chance of weaning outcomes.",[53],"Ventilated Patient in Intensive Care","2026-06-02",{"date":56,"type":57},"2026-06-05","ACTUAL",{"date":59,"type":57},"2026-01-01",{"date":61,"type":48},"2026-08-01",{"name":5,"class":6},1]