This study aims to assess the efficacy of intraoperative wound irrigation with iodine-containing and chlorhexidine-containing solutions in reducing bacterial colonization during spine surgery, and to determine which solution is more effective. Additionally, we aim to evaluate any side effects associated with the use of these two antiseptic solutions for wound irrigation.
Patients who were diagnosed with lumbar spinal stenosis need to undergo posterior lumbar decompression with fusion surgery.
People who are allergic to disinfectants (Providine or CHG)
The surgical site has been operated before.
Patients under active infection status.
Parallel
Povidone-iodine solution; chlorhexidine gluconate
DrugBefore wound closure, each group will undergo different irrigation solutions for soaking the wound for three minutes followed by rinsing with copious saline.
Bacteria culture and Polymerase chain reaction exam
Samples from deep and superficial tissues and implants will be taken for bacterial culture and PCR analysis. Positive means bacterial growth.
Post operative infection
Patient develops symptomatic wound infection will be recorded
Click on the lead sponsor to view all of their trials.
