Effects of Exercise Timing on Sleep Quality

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-30
SponsorCentre Hospitalier Universitaire de Saint Etienne

About this trial

Modern lifestyles are marked by a prevalence of sedentary behaviors and physical inactivity, which have been linked to numerous adverse health effects. While regular physical exercise is a well-established countermeasure, exercising in the late afternoon may paradoxically disrupt deep sleep due to increased core body temperature. Inactive and sedentary individuals, who often have impaired autonomic function compared to endurance-trained athletes, may be particularly susceptible to these negative effects, potentially resulting in compromised thermoregulation and exacerbated disruptions to deep sleep, a critical stage of sleep essential for overall recovery. Therefore, this study aims to investigate the impact of aerobic exercise performed in the late afternoon versus morning on: 1) deep sleep and sleep onset latency; and 2) core body temperature and its autonomic regulatory mechanisms on endurance-trained and inactive-sedentary people.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Group "Inactive" :No regular exercise practice (inactive people that don't follow the WHO recommendations) and have sedentary behaviors

Group "Active": Regular exercise (athletes that are specialized in aerobic exercise, with more than 300 minutes per-week over 6 months and practice at regional level).

Disqualifiers

Have sleep disorders medically diagnosed or detected by sleep forms cutoffs (clinical insomnia by ISI, severe risk of obstructive sleep apnea by Stop-Bang, bad sleep quality by PSQI.

Have a diagnosed mental health condition requiring treatment

Have renal, respiratory, cardiovascular or neuromuscular disease medically diagnosed.

Be pregnant or breastfeeding

Trial design

Design model

Crossover

Treatments tested in this trial

  • Aerobic Exercise

    Other intervention

    The exercise consists of running on a treadmill at 90% of maximum aerobic speed (MAS) for 30 minutes, followed by 12% increments every 5 minutes, until exhaustion (a "time-to-exhaustion" type of exercise).

Treatment groups

42 Participants
are divided into 2 treatment groups
Group A: "Inactive-sedentary" groupActive comparator 1 intervention
Group B: "Active" groupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Duration of deep slow-wave sleep

Evaluation of the duration of deep slow-wave sleep (N3 stage) quantified by the EEG signal from polysomnography (Nox A1, Resmed®, USA).

Time frame
Once a month for 3 months

Secondary outcomes

1

Assessment of core temperature

Assessment of core temperature until the end of the sleep period will be measured using gastrointestinal telemetric pills (eCelsius, Bodycap®, France).

Time frame
Once a month for 3 months
2

Evaluation of autonomic nervous system thermoregulation

Evaluation of autonomic nervous system thermoregulation through time-domain (R-R intervals in ms)

Time frame
Once a month for 3 months
3

Evaluation of autonomic nervous system thermoregulation

Evaluation of autonomic nervous system thermoregulation through frequency- domain parameters (in Hz)

Time frame
Once a month for 3 months
4

Complementary sleep evaluation

Complementary sleep evaluation through analysis of duration of N1, N2, and REM stages (in Percentage of Total Sleep Time)

Time frame
Once a month for 3 months

Other outcomes

Sponsors and contacts

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