Effects of Isocapnic Respiratory Muscle Endurance Training in Healthy Adults

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorUniversity of British Columbia

About this trial

Respiratory muscle training (RMT) strengthens breathing muscles and may improve exercise performance and reduce breathlessness. However, different training methods and devices create controversy in the field. Two main types of RMT exist: inspiratory muscle training (IMT) and respiratory endurance training, like voluntary isocapnic hyperpnea (VIH). While IMT is well-studied, the impact of VIH on breathlessness remains unclear. This study will use the Canadian-developed BreathWayBetter device to examine how 5 weeks of VIH affects breathing discomfort and muscle function. Findings may help personalize RMT for athletes and clinical patients, improving respiratory care and exercise tolerance.

Eligibility criteria

Qualifiers

18-55 years of age (inclusive)

Male or Female (biological sex)

Body mass index greater than 18 or less than 30 kg/m2

Normal pulmonary function: FEV1/FVC > 0.70 and FEV1 ≥ 80%

Disqualifiers

Currently smoke, vape, or use cannabis, or have a history of frequent smoking, vaping or cannabis use

History of, or current symptoms of cardiopulmonary (i.e., lung and/or heart) disease (excluding controlled asthma)

Heart problem; a serious infection within the body; a neuromuscular (nerve to muscle) or musculoskeletal (muscle, ligament and/or bone) disorder; or other health problem that will be made worse with exercise testing

Contraindications to exercise testing defined as anything that would prevent exercise under proper and safe conditions (e.g. a problem with the heart or lungs, muscle or bone injury, a serious infection)

Trial design

Treatments tested in this trial

  • Respiratory muscle endurance training
  • Sham respiratory muscle endurance training

Treatment groups

32 Participants
are divided into 2 treatment groups

Sponsors and collaborators