Effects of Physiotherapy on Ultrasound and Clinical Parameters in Women With Dysmenorrhea

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-50
SponsorVrije Universiteit Brussel

About this trial

Dysmenorrhea affects up to 90% of women of reproductive age and represents a significant public health concern. Beyond prostaglandin-mediated uterine contractions, dysmenorrhea involves central sensitization mechanisms and myofascial components, including abdominal trigger points. Despite growing interest in physiotherapy for chronic pelvic pain, objective data on tissue-level changes induced by manual therapy remain scarce.

This randomized single-blind sham-controlled trial aims to evaluate the effects of abdominal manual mobilization techniques on (1) tissue stiffness measured by shear wave elastography at the uterine cervix and bilateral abdominal regions, and (2) clinical outcomes including pain intensity and quality of life in women with dysmenorrhea, with or without endometriosis.

Participants will be randomly assigned to either a treatment group receiving standardized abdominal manual therapy or a sham group receiving superficial manual contact. Assessments will be conducted over three menstrual cycles using shear wave elastography, the Numeric Rating Scale (NRS), and the SF-36 questionnaire.

Eligibility criteria

Qualifiers

female sex

aged 18 to 50 years

clinical diagnosis of dysmenorrhea (cyclic pelvic pain during menstruation)

Disqualifiers

Pregnancy or breastfeeding

Delivery less than 1 year prior to enrollment

History of abdominal or pelvic surgery within the past 3 months

Diagnosis of fibromyalgia, diabetes, or cancer

Trial design

Treatments tested in this trial

  • Abdominal manual mobilization
  • Sham manual contact

Treatment groups

80 Participants
are divided into 2 treatment groups

Sponsors and collaborators