Effects of Replacing High Protein Foods in People With Chronic Kidney Disease
ConditionChronic Kidney Disease Stage 3
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-70
SponsorIndiana University
About this trial
The goal of this crossover clinical trial is to explore the effects of red meat intake on serum and fractional urinary excretion of uremic toxins including trimethylamine N-oxide in people with chronic kidney disease.
Eligibility criteria
Qualifiers
Age 40-70 years
Male or postmenopausal female
Stage 3 CKD (eGFR between 30-59ml/min/1.73m² by the CKD-EPI equation (without race correction)).
If eGFR is greater than or equal to 45ml/min/1.73m² then albuminuria must be greater than 300mg/g creatinine by spot urine.
Disqualifiers
Hemoglobin A1c greater than 7% within previous six months
Treatment with metformin or insulin within previous three months
Blood pressure greater than 150/100 mmHg from chart of home on at least two occasions in prior month (can be inclusive of screening visit)
Change in cardiovascular and/or hypertension medication in the last 30 days
Trial design
Treatments tested in this trial
- Controlled dietary intervention
Treatment groups
15 Participants
are divided into 2 treatment groupsSponsors and collaborators
Indiana University
Lead sponsor
National Center for Advancing Translational Sciences (NCATS)
Collaborator
Source ClinicalTrials.gov