[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630980":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":11,"centralContacts":11,"locations":11,"responsibleParty":35,"collaborators":11,"id":39,"slug":11,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":11,"eligibilityCriteria":44,"healthyVolunteers":40,"sex":45,"minAge":46,"maxAge":11,"enrollmentInfo":47,"targetDuration":11,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":11,"overallStatus":56,"whyStopped":11,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":11},{"fullName":5,"class":6},"Spital Thurgau AG","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Low-load strength training with intermittent application of pressure cuffs","ACTIVE_COMPARATOR",null,[13],"Diagnostic Test: Application of pressure cuffs during strength training",{"label":15,"type":10,"description":11,"interventionNames":16},"Low-load endurance training with alternating continuous application of pressure cuffs",[17],"Diagnostic Test: Application of pressure cuffs during endurance training",{"label":19,"type":20,"description":11,"interventionNames":21},"Conventional clinical rehabilitation program without the use of pressure cuffs","PLACEBO_COMPARATOR",[22],"Diagnostic Test: Conventional clinical rehabilitation program without the use of pressure cuffs",[24,29,33],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"DIAGNOSTIC_TEST","Application of pressure cuffs during strength training","Pre\u002FPost comparison of mitochondrial capacity of the m. vastus lateralis muscle and muscle morphology between the groups.",[9],{"type":25,"name":30,"description":31,"armGroupLabels":32,"otherNames":11},"Application of pressure cuffs during endurance training","Pre\u002FPost comparison of mitochondrial capacity of the m. vastus lateralis muscle and muscle morphology between the groups",[15],{"type":25,"name":19,"description":31,"armGroupLabels":34,"otherNames":11},[19],{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Hannes Bossung","Master of Science","100630980",false,"NCT07494721","Effects of Training With a Pressure Cuff on Cellular Energy Activity","Influence of Short-Term Conventional Cuff-Assisted Training on Mitochondrial Capacity: A Non-Invasive Investigation","Inclusion:\n\n* Medically confirmed generalized deconditioning with reduced muscle strength\n* Medical certification of suitability for functional lower-extremity strength training\n* Written informed consent after an adequate reflection period\n\nExclusion:\n\n* Unstable arrhythmias, myocardial ischemia, symptomatic blood pressure drops or hypertension (\\>160\u002F100 mmHg despite medication)\n* History of thrombosis or acute swelling\u002Fskin discoloration of the legs\n* Dizziness, confusion, cyanosis, or unexplained fatigue\n* Participant's wish to withdraw or not participate","ALL","18 Years",{"count":48,"type":49},51,"ESTIMATED","INTERVENTIONAL",[52],"NA","This study investigates low-load, cuff-assisted training to improve mitochondrial capacity. The intervention is carried out using automated pressure cuffs, applying an individualized pressure of 70% of the limb occlusion pressure. This approach reflects the current scientific consensus for safe and effective use in clinical populations.\n\nWithin a rehabilitation setting, two training modalities are compared: intermittent strength training and alternating continuous endurance training. Muscle oxygen saturation is measured non-invasively using near-infrared spectroscopy.",[55],"Physical Deconditioning","NOT_YET_RECRUITING","2026-03-26",{"date":59,"type":60},"2026-04-01","ACTUAL",{"date":62,"type":49},"2026-07",{"date":64,"type":49},"2026-12",{"name":5,"class":6}]