[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644087":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":28,"locations":38,"responsibleParty":54,"collaborators":58,"id":68,"slug":24,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":69,"sex":75,"minAge":76,"maxAge":24,"enrollmentInfo":77,"targetDuration":24,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":95,"overallStatus":99,"whyStopped":24,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Xuanwu Hospital, Beijing","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Mobile Stroke Unit Management","EXPERIMENTAL","ICH patients treated in the Mobile Stroke Unit",[13],"Other: Mobile Stroke Unit Management",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Management","ACTIVE_COMPARATOR","ICH patients receiving standard management",[19],"Other: Standard Management",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"MSU is a specialized stroke ambulance equipped with point of care lab, CT scanner, Telemedicine, enabling rapid diagnosis and prehospital management of acute stroke.\n\nPatients with suspected stroke undergo on-board CT imaging. Those diagnosed with intracerebral hemorrhage receive immediate prehospital blood pressure lowering.\n\nA standard treatment regime based on intravenous (IV) bolus of 25mg urapidil administered over 1 minute. For those patients initial systolic blood pressure 180, another 25mg urapidil bolus will be given if the systolic blood pressure level persists \\>150 after 5 minutes.",[9],null,{"type":6,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"A regular ambulance. The standard management by EMS includes Electrocardiographic（ECG）monitoring, blood glucose management, airway, respiration, and blood pressure control, complication management, intravenous access establishment and other emergency measures.\n\nPrehospital antihypertensive treatment is administered only in cases of severe hypertension (systolic blood pressure ≥220 mmHg), with blood pressure lowering initiated after in-hospital CT confirmation.",[15],[29,34],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Xinyu Wang, MD","CONTACT","86-159-6477-4581","wangxinyuneuron@163.com",{"name":35,"role":31,"phone":36,"phoneExt":24,"email":37},"Xiuhai Guo, MD, PhD","86-10-83198852","guoxhxuan@126.com",[39],{"facility":40,"status":24,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Xuanwu Hospital","Beijing","Beijing Municipality","100053","China","CN",{"type":47,"coordinates":48},"Point",[49,50],116.39723,39.9075,{"lat":50,"lon":49},[53],{"name":35,"role":31,"phone":36,"phoneExt":24,"email":37},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Xiuhai Guo,MD","Principal Investigator",[59,61,63,66],{"name":60,"class":6},"Beijing Emergency Medical Center",{"name":62,"class":6},"Huizhou Third People's Hospital, Guangzhou Medical University",{"name":64,"class":65},"Suzhou First People's Hospital","UNKNOWN",{"name":67,"class":65},"Nanyang nanshi Hospital","100644087",false,"NCT07665827","Efficacy and Safety of Antihypertensive Treatment With Mobile Stroke Units in Ultra-Early Intracerebral Hemorrhage","Efficacy and Safety of Antihypertensive Treatment With Mobile Stroke Units in Ultra-Early Intracerebral Hemorrhage: A Multicenter, Prospective, Cluster-Randomized, Open-Label, Blinded-Endpoint Clinical Trial","MSU-ICH","Inclusion Criteria:\n\n1. History and physical\u002Fneurological examination consistent with acute stroke.\n2. Age ≥18 years;\n3. Time from symptom onset to enrollment \\\u003C3 hours (onset defined as last known normal).\n4. Systolic blood pressure ≥150 mmHg and ≤220 mmHg;\n5. Pre-stroke modified Rankin Scale (mRS) score ≤2;\n6. Informed consent obtained from the subject or a legally authorized representative.\n\nExclusion Criteria:\n\n1. Glasgow Coma Scale (GCS) score ≤5.\n2. Contraindications to intensive blood pressure lowering, including severe arterial stenosis or high-grade stenotic valvular heart disease.\n3. Malignant disease or other serious primary illness with a life expectancy of \\\u003C3 months.\n4. Current participation in another interventional randomized clinical trial.","ALL","18 Years",{"count":78,"type":79},706,"ESTIMATED","INTERVENTIONAL",[82],"NA","MSU-ICH is a prospective, multicenter, Week-wise-randomized, open-label, blinded-endpoint (PROBE) clinical trial comparing ultra-early prehospital blood pressure lowering delivered by a Mobile Stroke Unit (MSU) with standard Emergency Medical Services (EMS) in patients with spontaneous intracerebral hemorrhage.",[85,86,87,88,89,90,91,92,93,94],"Nervous System Diseases","Cerebrovascular Disorders","Cardiovascular Diseases","Vascular Diseases","Hemorrhage","Intracranial Hemorrhages","Cerebral Hemorrhage","Cerebral Hemorrhage, Hypertensive","Stroke","Hemorrhagic Stroke, Intracerebral",[96,97,98],"intracerebral hemorrhage","mobile stroke units","Intensive blood pressure lowering","NOT_YET_RECRUITING","2026-06-18",{"date":102,"type":103},"2026-06-24","ACTUAL",{"date":105,"type":79},"2026-06",{"date":107,"type":79},"2028-07",{"name":5,"class":6},1]