Electroacupuncture Plus 5-HT3 Receptor Inhibitor for PONV Prevention in High-Risk Patients Undergoing Thoracoscopic Lung Cancer Surgery

ConditionPONV
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorShanghai Chest Hospital

About this trial

This prospective, randomized controlled study aims to evaluate the efficacy and safety of electroacupuncture combined with 5-HT3 receptor inhibitor for preventing postoperative nausea and vomiting (PONV) in high-risk patients undergoing thoracoscopic lung cancer surgery. The primary outcome is the incidence of PONV within 24 hours after surgery.

Eligibility criteria

Qualifiers

Age ≥ 18 years;

American Society of Anesthesiologists (ASA) physical status I-III;

Body mass index (BMI) 18-30 kg/m²;

Scheduled for elective video-assisted thoracoscopic surgery (VATS) lobectomy, segmentectomy, or wedge resection;

Disqualifiers

Severe systemic diseases, such as cardiovascular, hepatic, or renal abnormalities, or poor pulmonary function;

Subjects with cognitive dysfunction or psychological disorders;

History of previous esophageal or gastric surgery;

Hypersensitivity to acupuncture or any study medications;

Trial design

Treatments tested in this trial

  • Prophylactic administration of dolasetron
  • Electroacupuncture
  • Sham electroacupuncture

Treatment groups

204 Participants
are divided into 2 treatment groups

Sponsors and collaborators