[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100578263":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":18,"locations":24,"responsibleParty":37,"collaborators":41,"id":45,"slug":18,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":18,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":18,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":70,"whyStopped":18,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Brigham and Women's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Sleep restriction","EXPERIMENTAL","Participants undergo sleep restriction to 4 hours\u002Fnight",[13],"Behavioral: Sleep restriction",{"label":15,"type":16,"description":17,"interventionNames":18},"Control condition","NO_INTERVENTION","Participants undergo the control condition (no sleep restriction)",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"BEHAVIORAL","Participants will be asked to sleep 4h\u002Fnight",[9],[25],{"facility":5,"status":18,"city":26,"state":27,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":18},"Boston","Massachusetts","02115","United States","US",{"type":32,"coordinates":33},"Point",[34,35],-71.05977,42.35843,{"lat":35,"lon":34},{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Charles A. Czeisler, PhD, MD","Professor of Sleep Medicine",[42],{"name":43,"class":44},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","NIH","100578263",false,"NCT06809023","Evaluation of Sex Differences in Glucose Metabolism in Response to Sleep Curtailment","Inclusion Criteria:\n\n* Healthy adults with conventional sleep-wake timing\n* Non-smokers\n* Completion of medical, psychological, and sleep screening tests\n* Able to spend 5 consecutive days\u002Fnights in the laboratory on two separate occasions (total of 10 days\u002Fnights in the laboratory)\n* Women must have a recent history of regular menstrual cycles\n\nExclusion Criteria:\n\n* History of neurological or psychiatric disorder\n* History of sleep disorder or regular use of sleep-promoting medication\n* Current prescription, herbal, or over-the-counter medication use including hormonal birth control\n* Traveling across 2 or more time zones within past 3 months\n* Donating blood within past 8 weeks\n* Worked night or rotating shift work within past year\n* Hearing impairment, visual impairment\n* History of eye trauma or surgery\n* Drug or alcohol dependency",true,"ALL","20 Years","40 Years",{"count":55,"type":56},32,"ESTIMATED","INTERVENTIONAL",[59],"NA","The goal of this study is to learn whether insufficient sleep affects glucose metabolism differently in healthy men and women.",[62,63,64],"Sleep Deprivation","Sex Differences","Glucose Tolerance",[66,67,68,69],"glucose metabolism","sleep deprivation","sex differences","GLP-1","NOT_YET_RECRUITING","2025-12-09",{"date":73,"type":74},"2025-12-10","ACTUAL",{"date":76,"type":56},"2026-04",{"date":78,"type":56},"2029-02",{"name":5,"class":6},1]