[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100389798":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":64,"collaborators":26,"id":66,"slug":26,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":26,"eligibilityCriteria":70,"healthyVolunteers":67,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":26,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":42,"whyStopped":26,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Yale University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Vitamin D Supplement","EXPERIMENTAL","Patients will take vitamin D tablet with 4,000IU daily for 6 months.",[13],"Drug: Vitamin D 4000IU daily",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Patients will take placebo for 6 months",[19],"Drug: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Vitamin D 4000IU daily","Randomized to receive vitamin D 4000IU daily",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Randomized to placebo daily",[15],[31],{"name":32,"affiliation":5,"role":33},"Alla Vash-Margita, MD","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":26,"email":38},"CONTACT","203-785-4010","alla.vash-margita@yale.edu",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Yale New Haven Children's Hospital","RECRUITING","New Haven","Connecticut","06510","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-72.92816,41.30815,{"lat":52,"lon":51},[55,58,62],{"name":56,"role":36,"phone":57,"phoneExt":26,"email":38},"Alla Vash-Margita, Principal Investigator, MD","203-785-7409",{"name":59,"role":36,"phone":60,"phoneExt":26,"email":61},"Kathleen Miclette, nurse coordinator, RN","203-444-3720","kathleen.miclette@ynhh.org",{"name":63,"role":33,"phone":26,"phoneExt":26,"email":26},"Alla Vash-Margita, Associate Professor, MD",{"type":65,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100389798",false,"NCT04355572","Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)","Inclusion Criteria:\n\n\\- Postmenarchal adolescent females aged 13-21 who meet modified Rotterdam criteria for PCOS, with a serum vitamin D level between 6-29 ng\u002FmL.\n\nExclusion Criteria:\n\n* Other causes for hyperandrogenism,\n* Chronic renal diseases,\n* Acquired or inherited calcium and vitamin D metabolic disorders.","FEMALE","13 Years","21 Years",{"count":75,"type":76},60,"ESTIMATED","INTERVENTIONAL",[79],"NA","This study is a double blind, placebo controlled, randomized trial of study subjects with PCOS and low vitamin D to 2 groups- placebo and vitamin D replacement. Participants and investigators will be blinded to treatment modality until the end of the trial period",[82,83],"Polycystic Ovarian Syndrome in Adolescent Females","Vitamin D Deficiency",[85],"Anti-Mullerian Hormone (AMH)","2026-02-19",{"date":88,"type":89},"2026-02-23","ACTUAL",{"date":91,"type":76},"2026-05",{"date":93,"type":76},"2027-12-01",{"name":5,"class":6},1]