[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100541946":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":20,"locations":27,"responsibleParty":40,"collaborators":11,"id":42,"slug":11,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":43,"sex":48,"minAge":49,"maxAge":11,"enrollmentInfo":50,"targetDuration":11,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":11,"overallStatus":59,"whyStopped":11,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"GCS Ramsay Santé pour l'Enseignement et la Recherche","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Skin biopsy","EXPERIMENTAL",null,[13],"Procedure: skin biopsy",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"PROCEDURE","skin biopsy","Samples will be taken under local anaesthetic (after injection of 1 cc of Xylocaine without adrenaline) using a 4 mm diameter dermal biopsy punch. The biopsy will be performed on the buttocks. Fragments are stored in 15-mL polypropylene tubes in PBS at 4°C.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":25,"email":26},"Geoffroy NOURISSAT, MD","CONTACT","07 69 99 67 30","33","gnourissat@wanadoo.fr",[28],{"facility":29,"status":11,"city":30,"state":11,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":11},"Clinique Maussins-Nollet","Paris","75019","France","FR",{"type":35,"coordinates":36},"Point",[37,38],2.3488,48.85341,{"lat":38,"lon":37},{"type":41,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100541946",false,"NCT06336473","Evaluation of the Effects of Cross Linking on the Biomechanical Characteristics of Skin Samples From Patients With Classic or Hypermobile Ehlers-Danlos Syndrome","SEDSKIN","Inclusion Criteria:\n\n* Patient aged 18 or over, having read and signed the consent form for participation in the study\n* Patient with classic or hypermobile Ehlers-Danlos syndrome\n* Regularly followed-up at the non-vascular Ehlers-Danlos Syndrome Reference Center at Garches Hospital.\n\nExclusion Criteria:\n\n* Patient under court protection, guardianship or curatorship\n* Pregnant or breast-feeding patient\n* Patient not affiliated to the French social security system\n* Impossibility of giving the subject informed information and\u002For written informed consent: dementia, psychosis, disturbed consciousness, non-French-speaking patient\n* Contraindication to anaesthesia or allergy to local anaesthetic product","ALL","18 Years",{"count":51,"type":52},28,"ESTIMATED","INTERVENTIONAL",[55],"NA","The main aim of this study is to evaluate the effect of cross linking on the elasticity of skin samples from patients with non-vascular Ehlers-Danlos Syndrome (hEDS or cEDS).",[58],"Ehlers-Danlos Syndrome","NOT_YET_RECRUITING","2024-06-21",{"date":62,"type":63},"2024-06-24","ACTUAL",{"date":65,"type":52},"2024-09-03",{"date":67,"type":52},"2025-07-31",{"name":5,"class":6},1]