[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635848":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":28,"locations":10,"responsibleParty":34,"collaborators":10,"id":37,"slug":10,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":42,"eligibilityCriteria":43,"healthyVolunteers":38,"sex":44,"minAge":45,"maxAge":46,"enrollmentInfo":47,"targetDuration":10,"studyType":50,"phases":10,"briefSummary":51,"conditions":52,"keywords":54,"overallStatus":57,"whyStopped":10,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":10},{"fullName":5,"class":6},"National Institute of Cardiology, Laranjeiras, Brazil","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ANOCA",null,"Symptomatic Group (ANOCA): n = 40 patients with stable angina and non-obstructive coronary arteries.",[13],"Procedure: Investigation of Systemic Endothelial Microvascular Function",{"label":15,"type":10,"description":16,"interventionNames":17},"CONTROL","Control Group: n = 20 age-matched women without chest pain and without CAD.",[13],[19],{"type":20,"name":21,"description":21,"armGroupLabels":22,"otherNames":23},"PROCEDURE","Investigation of Systemic Endothelial Microvascular Function",[9,15],[24,25,26,27],"Myocardial Perfusion Imaging","Sublingual videomicroscopy","Invasive coronary flow determination","Cutaneous Laser Speckle Contrast Imaging",[29],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Eduardo Tibirica, MD, PhD","CONTACT","+55-21-99914-6075","etibi@uol.com.br",{"type":35,"investigatorFullName":30,"investigatorTitle":36,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Senior Researcher","100635848",false,"NCT07558018","Evaluation of the Systemic Microcirculation as a Surrogate for Coronary Microcirculation in Women With ANOCA","Evaluation of the Systemic Microcirculation as a Surrogate for Coronary Microcirculation in Women With ANOCA: Insights Into Pathophysiology and Diagnosis Using Noninvasive, Innovative Techniques (NOCAWT)","NOCAWT","Inclusion Criteria:\n\n* Age 18-65 years\n* Anginal chest pain\n\nExclusion Criteria:\n\n* Malignant neoplasms\n* Autoimmune diseases\n* Acute systemic diseases\n* Pregnancy or lactation\n* Iodine allergy\n* CAD on invasive coronary angiography or coronary computed tomography angiography (CCTA)","FEMALE","18 Years","65 Years",{"count":48,"type":49},60,"ESTIMATED","OBSERVATIONAL","The primary objective of this project is to validate a multi-modal systemic microvascular phenotyping platform-combining Laser Speckle Contrast Imaging (LSCI) and Sublingual Handheld Videomicroscopy (IDF imaging)-as a non-invasive surrogate for coronary microvascular function in women with ANOCA (Angina with Non-Obstructive Coronary Arteries). We aim to demonstrate that systemic microvascular signatures (microvascular reactivity and density) can predict coronary endotypes with high accuracy, potentially reducing the need for invasive diagnostics.",[53],"Angina, Microvascular",[55,56,25],"microcirculation","Laser Speckle Contrast Imaging","NOT_YET_RECRUITING","2026-05-02",{"date":60,"type":61},"2026-05-05","ACTUAL",{"date":63,"type":49},"2026-08",{"date":65,"type":49},"2029-12",{"name":5,"class":6}]