Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-35
SponsorVirginia Commonwealth University

About this trial

The purpose of this research study is to examine the role oxidants, substances produced in the blood that can damage blood vessel function, may play in blood vessel function in healthy individuals as well as individuals with mental health disorders (posttraumatic stress disorder (PTSD) and/or generalized anxiety disorder (GAD)).

Eligibility criteria

Qualifiers

apparently healthy and free of overt cardiovascular, pulmonary, or metabolic disease

for PTSD group, a score of ≥ 33 on PCL-5 checklist

for GAD group, a score of ≥ 10 on the GAD-7 self-report scale and < 33 on the PCL-5 checklist

for Healthy Control group, a score of ≤ 10 on the GAD-7 self-report scale and < 33 on the PCL-5 checklist

Disqualifiers

taking medications that could influence cardiovascular function

current smokers who have recently quit smoking

illicit drug use or excessive alcohol consumption

pregnant women

Trial design

Treatments tested in this trial

  • Antioxidant
  • Placebo

Treatment groups

720 Participants
are divided into 2 treatment groups