Expanded Access for Vepugratinib (LY3866288) in Participants With Fibroblast Growth Factor Receptor 3 (FGFR3) Altered Solid Tumors

Trial statusAvailable
Trial phaseNot listed
Trial typeExpanded Access
Biological sexAll
Age18+
SponsorEli Lilly and Company

About this trial

The treating physician/investigator contacts Lilly when, based on their medical opinion, a patient meets the criteria for inclusion in the expanded access program.

Eligibility criteria

Qualifiers

Have metastatic urothelial carcinoma (UC) or other solid tumor with a qualifying fibroblast growth factor receptor 3 (FGFR3) genetic alteration.

Have exhausted other approved treatments, including erdafitinib for UC.

Are not eligible for an ongoing vepugratinib clinical trial

Disqualifiers

Currently enrolled in an ongoing clinical study of vepugratinib

Have a known severe (greater than or equal to (≥) Grade 3) hypersensitivity to any component or excipient of vepugratinib.

Current evidence of corneal keratopathy or retinal disorder confirmed by ocular examination. Exception: Individuals with asymptomatic ophthalmic conditions assessed by the investigator to pose minimal risk.

Are pregnant, breastfeeding, or intent to become pregnant during the study or within 6 months of the last dose of study intervention.

Trial design

Treatments tested in this trial

  • Vepugratinib

Treatment groups

No treatment groups listed

Locations

This trial has no locations

Sponsors and collaborators