[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610526":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":28,"centralContacts":33,"locations":40,"responsibleParty":56,"collaborators":58,"id":65,"slug":12,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":72,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":12,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":43,"whyStopped":12,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"King's College London","OTHER",[8,13,19],{"label":9,"type":10,"description":11,"interventionNames":12},"No application of product and no massage","NO_INTERVENTION","No application of product and no massage.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Twice-Weekly Massage with Product","EXPERIMENTAL","Application of product containing oil- and aqueous-based components + skin massage twice a week",[18],"Other: Skin Massage with Product",{"label":20,"type":15,"description":21,"interventionNames":22},"Daily Massage with Product","Application of product containing oil- and aqueous-based components + skin massage daily",[18],[24],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":12},"Skin Massage with Product","Application of product containing oil- and aqueous-based components to baby's skin followed by a standardized massage.",[20,14],[29],{"name":30,"affiliation":31,"role":32},"Carsten Flohr","Guy's and St Thomas' NHS Foundation Trust","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":38,"email":39},"Preeti Khurana","CONTACT","020 7188 7188","57716","gstt.cutie.study@nhs.net",[41],{"facility":42,"status":43,"city":44,"state":12,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"St. Thomas' Hospital","RECRUITING","London","SE1 7EH","United Kingdom","UK",{"type":49,"coordinates":50},"Point",[51,52],-0.12574,51.50853,{"lat":52,"lon":51},[55],{"name":35,"role":36,"phone":37,"phoneExt":38,"email":39},{"type":57,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR",[59,60,62],{"name":31,"class":6},{"name":61,"class":6},"Rosetrees Trust",{"name":63,"class":64},"Stoneygate Trust","UNKNOWN","100610526",false,"NCT07228728","Exploring the Cutaneous Immune Response to Skin Massage in Early Life","A Randomised Controlled Trial to Investigate How Regular Skin Massage Impacts the Immune System in Early Life","CUTIE","Inclusion Criteria:\n\n1. Healthy babies born at term up to 6 months old\n2. Ability of parents\u002Fguardians\u002Fcaregivers to provide written informed consent for study participation\n3. Willingness of parents\u002Fguardians\u002Fcaregivers to comply with all study requirements.\n\nExclusion Criteria:\n\n1. Parents\u002Fguardians\u002Fcaregivers unable to give informed consent.\n2. Personal history of inflammatory skin disease (in particular atopic dermatitis)\n3. Active involvement in another interventional research study",true,"ALL","0 Months","6 Months",{"count":77,"type":78},109,"ESTIMATED","INTERVENTIONAL",[81],"NA","This project aims to study whether regular skin massage in babies induces cutaneous inflammation and whether this inflammatory response is amplified in those receiving daily (vs bi-weekly or no) skin massage over an 8 week period. Specifically, it aims to:\n\n1. Establish if massage increases \u002Fdecreases immune signals in the skin.\n2. Clarify if the effects of massage are enhanced with the frequency of massage. 3.) Assess changes in skin biology as a consequence of skin massage. 4.) Determine if massage impacts skin barrier function in the early years of life.",[84],"Skin Massage",[86,87,88,89,90,91,92,93,94],"Massage","Early life","dermatology","Immune System","Immune Response","Infant Development","Skin barrier","Microbiome","Interstitial Skin fluid","2026-02-09",{"date":97,"type":98},"2026-02-11","ACTUAL",{"date":100,"type":98},"2026-01-02",{"date":102,"type":78},"2027-04-30",{"name":5,"class":6},1]