[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629403":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":24,"responsibleParty":48,"collaborators":10,"id":51,"slug":10,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Fu Jen Catholic University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Case group",null,"Pre-COPD or COPD stages I-IV as per the 2023 GOLD guidelines",{"label":13,"type":10,"description":14,"interventionNames":10},"Control group","healthy controls",[16],{"name":17,"affiliation":5,"role":18},"Ke-Yun Chao, PhD","PRINCIPAL_INVESTIGATOR",[20],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","+886-905-301-879","ck_qq@hotmail.com",[25,40],{"facility":26,"status":10,"city":27,"state":10,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Cardinal Tien Hospital","New Taipei City","23148","Taiwan","TW",{"type":32,"coordinates":33},"Point",[34,35],121.45703,25.06199,{"lat":35,"lon":34},[38],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":39},"ck_qq@hotmail.con",{"facility":41,"status":10,"city":27,"state":10,"zip":42,"country":29,"countryCode":30,"cosmosGeoPoint":43,"geoPoint":45,"contacts":46},"Fu Jen Catholic University Hospital, Fu Jen Catholic University","24352",{"type":32,"coordinates":44},[34,35],{"lat":35,"lon":34},[47],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":39},{"type":18,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Ke-Yun, Chao","Assistant Professor","100629403",false,"NCT07474220","Expression of SLC25A48 in Chronic Obstructive Pulmonary Disease","Association Between SLC25A48 Expression and Chronic Obstructive Pulmonary Disease Progression","Inclusion Criteria:\n\n* pre-COPD or COPD stages I-IV as per the 2023 GOLD guidelines (case group)\n* healthy individuals without chronic diseases or major medical conditions\n\nExclusion Criteria:\n\n* diagnosed with neuromuscular diseases\n* experienced respiratory disease exacerbation requiring emergency care or hospitalization in the past three months\n* assessed by a physician to have severe malnutrition or a significantly low BMI\n* continuously taking folic acid supplements\n* willing to receive or have already received self-paid nutrition clinic services at this hospital",true,"ALL","18 Years",{"count":61,"type":62},180,"ESTIMATED","OBSERVATIONAL","This study aims to investigate the expression level of SLC25A48, a mitochondrial choline transporter, in peripheral blood mononuclear cells of patients with chronic obstructive pulmonary disease, and to analyze its correlation with inflammatory markers and choline metabolic byproducts.",[66],"Chronic Obstructive Pulmonary Disease",[68,69,70,71,72],"Chronic obstructive pulmonary disease","Mitochondrial choline transport","SLC25A48","Inflammatory markers","Choline metabolism","NOT_YET_RECRUITING","2026-03-14",{"date":76,"type":77},"2026-03-17","ACTUAL",{"date":79,"type":62},"2026-04-01",{"date":81,"type":62},"2026-12-31",{"name":5,"class":6},2]