Eye-Brain-Kidney in CKD
ConditionChronic Kidney Diseases
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorBeijing Friendship Hospital
About this trial
The goal of this observational study is to learn about the interaction between the eyes, brain, and kidneys in adult patients with Chronic Kidney Disease (CKD). The main question it aims to answer is:
Do changes in the brain's network connectivity and the retina's blood vessels correlate with cognitive decline and kidney function in CKD patients? Participants with CKD who are already undergoing clinical care will complete cognitive tests and questionnaires, have non-invasive MRI scans of their brain and kidneys, and undergo non-invasive eye imaging (OCT/OCTA) of their retinas.
Eligibility criteria
Qualifiers
Aged 18-70 years.
Patients clinically diagnosed with CKD stages 1-5.
No contraindications for MRI examination (e.g., cardiac pacemaker, claustrophobia, cochlear implant, hearing aid, coronary stents implanted before 2015) and able to complete the MRI scan.
Disqualifiers
Patients with recent or prior cerebral hemorrhage or cerebral infarction.
History of epileptic seizures or psychiatric disorders.
Patients with claustrophobia.
Pregnant or lactating patients.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Source ClinicalTrials.gov