Factors Affecting Sensory and Motor Learning
ConditionBasic Science
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorIndiana University
About this trial
How participants perceive the position of their own hand in various contexts will be examined. This will include changing the visual display to suggest the hand is in a slightly different position, and asking participants to indicate where they think it is by pointing with their other hand.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Between the ages of 18-45 years old
Right-handed.
Covid has been found to have neurological effects in some people, but mostly the effects on sensorimotor control and neurophysiology are unknown. So we will only include individuals who report being free of Covid symptoms in week preceding testing.
Disqualifiers
Past or present history of seizure, stroke, any brain or peripheral nerve disease, severe head trauma, or spinal cord surgery.
Learning or attention conditions such as ADHD.
Orthopedic or pain conditions, or a history of seriously injured bones, joints or muscles in either arm.
Lack of normal or corrected-to-normal vision.
Trial design
Design model
Parallel
Treatments tested in this trial
Explanatory diagram
BehavioralParticipant is told there will be a mismatch between their target finger and the visual indicator of target finger position. They will be shown a diagram explaining this.
Direct vision
BehavioralFoamboard under mirror removed, making the mirror see-through and the hand directly visible. Mismatch between target hand and visual indicator will be directly visible.
Movement feedback, target hand
BehavioralAfter the participant points at each target, a cursor indicating final pointing position will be displayed briefly. The visual indicator of the target hand will be displaced.
Movement feedback, pointing hand
BehavioralAfter the participant points at each target, a cursor indicating final pointing position will be displayed briefly. The visual indicator of the target hand will not change, but the cursor indicating pointing hand position will change.
No movement feedback
BehavioralThe visual indicator of the target hand will be displaced, but there will be no cursor to indicate the pointing hand's position.
Attend to the targets
BehavioralParticipants will not be told anything about the visuo-proprioceptive mismatch. Instead, they will be asked simply to attend to the target positions.
Treatment groups
300 Participants
are divided into 6 treatment groups6
Treatment groupsSee each treatment group below.
Group A: Conscious awareness: No informationSham comparator 1 intervention
Group B: Conscious awareness: Explanatory diagramExperimental treatment 1 intervention
Group C: Conscious awareness: Direct vision of handExperimental treatment 1 intervention
Group D: Movement feedback: No feedbackSham comparator 1 intervention
Group E: Movement feedback: Target handExperimental treatment 1 intervention
Group F: Movement feedback: Pointing handExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Realignment
Measured by comparing where the subject points on a touchscreen when indicating perceived position of visual and proprioceptive targets early vs. late in the behavioral task.
Time frame
1 daySecondary outcomes
1
Visuo-proprioceptive weighting
The degree to which participant relies on vision vs. proprioception when both are available. Measured by comparing where the subject points on a touchscreen when indicating perceived position of visual vs. proprioceptive targets.
Time frame
1 day2
Target estimation variance
Variance with which participant estimate visual and proprioceptive target positions. Computed from where subjects point at targets on a touchscreen.
Time frame
1 day.Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Indiana University
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborator
Source ClinicalTrials.gov