[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100494962":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":20,"locations":30,"responsibleParty":52,"collaborators":54,"id":64,"slug":19,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":65,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":19,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":33,"whyStopped":19,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Associazione Italiana per lo Studio del Pancreas","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Saliva testing swab","Subjects with familiarity with pancreatic cancer enrolled into the IRFARPC registry (NCT04095195) will be submitted to buccal swab for saliva-based genetic testing",[12],"Genetic: Saliva swab testing",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"GENETIC","Saliva swab testing","41 pancreatic cancer predisposition genes will be tested through a saliva-based swab",[9],null,[21,26],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Erica Secchettin, PharmD","CONTACT","0458126254","familiarita.aisp@gmail.com",{"name":27,"role":23,"phone":28,"phoneExt":19,"email":29},"AISP Association","340 2713112","aisp.ricerca@gmail.com",[31],{"facility":32,"status":33,"city":34,"state":19,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Chirurgia generale e del Pancreas Azienda Ospedaliera Universitaria Integrata","RECRUITING","Verona","37136","Italy","IT",{"type":39,"coordinates":40},"Point",[41,42],10.9938,45.43854,{"lat":42,"lon":41},[45,49],{"name":46,"role":23,"phone":47,"phoneExt":19,"email":48},"Salvatore Paiella, MD, PhD","+390458126009","salvatore.paiella@univr.it",{"name":22,"role":23,"phone":50,"phoneExt":19,"email":51},"+390458126254","erica.secchettin@univr.it",{"type":53,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR",[55,58,60,62],{"name":56,"class":57},"General and Pancreatic Surgery Unit, University of Verona","UNKNOWN",{"name":59,"class":57},"Fondazione Valsecchi",{"name":61,"class":57},"Associazione Oltre La Ricerca",{"name":63,"class":57},"Genomica srl","100494962",false,"NCT05724992","Familial Pancreatic Cancer PROPHilation Program in Italy","Standardised Genetic Profiling of Subjects Belonging to the Italian Multicenter Registry of Prospective Surveillance of Subjects at Genetic Risk of Pancreatic Cancer","PROPH-ITA","Inclusion Criteria:\n\n* Being enrolled on the IRFARPC registry\n* Having familiarity for pancreatic cancer (according to the IRFARPC criteria, Capurso et al. Dig Liv Dis, 2020)\n* Willingness to participate in saliva-swab-based genetic testing\n\nExclusion Criteria:\n\n\\- Already known genetic mutation","ALL","18 Years","80 Years",{"count":75,"type":76},3000,"ESTIMATED","INTERVENTIONAL",[79],"NA","The goal of the PROPH-ITA Study is to perform genetic testing in family members of pancreatic cancer patients who may have a genetic predisposition. The subjects belong to the Italian Registry of Families At Risk of Pancreatic Cancer (IRFARPC, #NCT04095195). This investigational study will assess the genetic background of subjects with familiarity with pancreatic cancer only.\n\nParticipants may accept to undergo genetic testing as part of the IRFARPC registry, through a saliva-swab-based 41-gene panel test.\n\nUp to 3,000 participants will be enrolled in this study.",[82],"Candidates for Hereditary Pancreatic Cancer Testing",[84,85,86,87,88],"Pancreatic Cancer","Pancreatic Cancer familiarity","Genetic profiling","Genetic predisposition","Pancreatic Cancer surveillance","2023-02-13",{"date":91,"type":92},"2023-02-15","ACTUAL",{"date":94,"type":92},"2022-12-20",{"date":96,"type":76},"2028-12-20",{"name":5,"class":6},1]