This is a single-arm feasibility study employing a pre-post design with a 12-week intervention period. The study utilizes a telehealth-assisted home-based resistance exercise program, with a structured progression from supervised to unsupervised sessions over 12 weeks.
Age: 55-80 years
Diabetes: Diagnosed T2DM with ≥5 years duration
Cognitive Status: Mild cognitive impairment as defined by Petersen criteria and confirmed by Montreal Cognitive Assessment (MoCA) scores of 18-25
Medication Stability: Stable medication regimen for at least 3 months
Diagnosis of movement disorders such as multiple sclerosis, parkinson's disease
Diagnosis of Alzheimer's disease,
Current diagnosis of severe depression, major psychiatric conditions such as bipolar disorder, psychosis, schizophrenia, or alcoholism that could affect the ability to understand and/or cooperate fully with the protocol.
Significant cerebral vascular disease