This pilot randomize trial tests the feasibility of administering two different exercise programs in people with knee osteoarthritis. One group receives the exercise program administered as usual, and the other group received the exercise program with resting intervals.
Age between 45 and 79 yo.
Clinical diagnosis of primary, early to moderate stage knee osteoarthritis.
BMI range < 35 kg/m2.
Sedentary lifestyle
Non-OA disease of the knee.
Advanced knee osteoarthritis
Knee injection in the past 3 months.
Major knee trauma/surgery in the past 5 years or previous knee surgery with hardware limiting cartilage assessment..
Parallel
Exercise with Rest
BehavioralParticipants in this arm exercise 3 times a week for 12 weeks. Exercise program consists of warm-up, strengthening exercises of the lower major extremity muscle groups, and aerobic training using a treadmill. These sessions include two 45 minute rest periods between exercises and take about two and a half hours.
Exercise without Rest
BehavioralParticipants in this arm exercise 3 times a week for 12 weeks. Exercise program consists of warm-up, strengthening exercises of the lower major extremity muscle groups, and aerobic training using a treadmill. These sessions include minimal resting periods between exercises and take about one hour.
Feasibility of recruitment
The number of eligible individuals who are randomized out of all eligible individuals.
Safety of interventions
The number of adverse events related to study participation in each arm
Adherence to Intervention
The number of intervention sessions attended out of the total number of intervention sessions prescribed in the study.
Study retention
The number of participants in each intervention arm who attend the follow-up assessment visit out of the number of participants randomized to each intervention arm.
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University of Pittsburgh
Lead sponsor
Carnegie Mellon University
Collaborator
