FIND HF Risk-guided Screening for Heart Failure - Pilot Study
ConditionHeart Failure
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40+
SponsorUniversity of Leeds
About this trial
The goal of this clinical trial is to learn if the FIND HF algorithm detection rates of heart failure during testing are higher amongst participants identified as high FIND-HF risk compared to those identified as low risk in a population identified as at risk of undiagnosed heart failure. The main questions it aims to answer are:
* Are people who are identified as high risk by the FIND-HF tool more likely to be diagnosed with heart problems during testing than those identified as low risk? * Are people identified as high risk by the FIND-HF tool more likely to show signs of heart problems during testing than those identified as low risk?? Researchers will compare patients in the high risk and low risk groups to see if more patients are detected with asymptomatic heart failure in the high risk group compared to the low risk group.
Participants will attend one visit at a local clinic where they will undergo an NT proBNP blood test which indicates heart failure and an echocardiogram to evaluate the heart's chambers, valves and overall function to help diagnose various heart conditions.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
Known diagnosis of HF
On the palliative care register
Unable to give written informed consent for participation in the study
Unable to adhere to the study requirements
Trial population
Patients identified at risk of developing Heart Failure by the FIND HF algorithm and are aged 40 and over, living in the Yorkshire area.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
FIND HF algorithm
Diagnostic testAlgorithm developed by the research team to identify patients at risk of heart failure that is currently undetected.
Treatment groups
475 Participants
are divided into 1 treatment groupGroup A: Patients at risk of developing Heart Failure1 intervention
Trial outcomes
Primary outcomes
1
To determine whether detection rates of a composite of asymptomatic LVSD, HFrEF, HFmREF, or HFpEF during diagnostics are higher amongst participants identified as high FIND-HF risk compared to those identified as low risk
Odds ratio of asymptomatic LVSD, HFrEF, HFmREF, or HFpEF detection rates from intervention in people identified as high HF risk compared with people identified as low HF risk
Time frame
Through study completion, an average of 12 months from date of enrolmentSecondary outcomes
1
To determine if components of composite outcome during diagnostics are higher amongst participants identified as high FIND-HF risk compared to those identified as low risk
Odds ratio for each component of the composite in in people identified as high HF risk compared with people identified as low HF risk
Time frame
Through study completion, an average of 12 months from date of enrolmentLocations
Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: