Fluoroless Conduction System Implant

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-100
SponsorImperial College London

About this trial

Conduction system pacing is a new way of stimulating the heart using pacemaker wires. Traditional pacemakers stimulate the heart muscle which causes disordered heart beats: the walls of the heart move at different times. This wears down the heart over time.

Conduction system pacemakers stimulate the heart's electrical system directly producing natural heart beats that are much less disordered. These pacemakers can be challenging to insert with different heart shapes, sizes and scars. This can increase procedure times and time exposed to xray as pacemakers are inserted using x-rays to guide where the lead is implanted.

This study aims to allow conduction system pacemakers to be implanted without the use of normal xray (fluoroscopy).

The investigators will create an anatomical shell of the heart using special plastic (mapping) catheters that is inserted within the heart from the groin. The investigators will use a special heart scanning (echo) catheter to see how the pacemaker wire is inserted into the heart muscle. The investigators will use MRI to confirm that the information we collect is accurate. Using this information the investigators will create a protocol to implant a lead that does not require xray, using only the mapping catheter.

Eligibility criteria

Qualifiers

Patients with a ventricular pacing indication: high grade atrioventricular block and symptomatic trifasicular, bifasicular block or left bundle branch block LBBB for cardiac resynchronisation therapy

Adults willing to take part (ages 18 - 100 years old)

Able to give consent.

Disqualifiers

Unable to give consent

Children age < 18 years and adults > 100 years old

Pregnant patients • As per standard of care, female patients of child-bearing age will have a urine pregnancy test prior to their procedure.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

75 Participants
are grouped into 3 trial groups

Locations

This trial has no locations

Sponsors and collaborators