Frailty and Health-related Quality of Life in Older Women With Breast Carcinoma

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age60+
SponsorAin Shams University

About this trial

This study addresses a critical gap in the care of older women with breast cancer, a population often underrepresented in clinical research despite their increased vulnerability to treatment-related complications. By examining the relationship between frailty and health-related quality of life (QOL), the study aims to provide evidence-based insights into how geriatric assessments can guide personalized treatment decisions, ensuring that therapeutic benefits outweigh risks. Given that older adults prioritize QOL over survival gains, understanding the impact of frailty on their well-being can help clinicians optimize care plans, reduce adverse outcomes, and improve overall patient-centered outcomes. The findings may also inform the integration of routine geriatric assessments in oncology practice, ultimately enhancing the management of older cancer patients in resource-limited settings like Egypt.

Eligibility criteria

Qualifiers

Females aged 60 years and older

Newly diagnosed with pathologically proven breast invasive ductal or lobular carcinoma

Disqualifiers

History of cognitive impairment or psychiatric disorders

Delirium during assessment using the Confusion Assessment Method (CAM test)

Initiation of chemotherapy before the baseline assessment

Severe hearing or visual impairment preventing completion of assessment

Trial design

Treatments tested in this trial

  • Comprehensive geriatric assessment
  • European Organization for Research and Treatment-Quality of life questionnaire
  • Clinical Frailty Scale

Treatment groups

100 Participants
are divided into 1 treatment group

Locations

This trial has no locations

Sponsors and collaborators