[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100558049":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":19,"locations":10,"responsibleParty":29,"collaborators":10,"id":33,"slug":10,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":36,"acronym":10,"eligibilityCriteria":37,"healthyVolunteers":38,"sex":39,"minAge":40,"maxAge":41,"enrollmentInfo":42,"targetDuration":10,"studyType":45,"phases":46,"briefSummary":48,"conditions":49,"keywords":10,"overallStatus":51,"whyStopped":10,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":10},{"fullName":5,"class":6},"South Valley University","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"one group",null,[12],"Device: narrow band ultraviolet-B",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"DEVICE","narrow band ultraviolet-B","vitiligo patients will recevie twice sessions per week",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Soheir Abdel-Hamid, MD","CONTACT","01066877343","soher.abdel-hamid@med.svu.edu.eg",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Basma Tito Abd Elhameed, MD","01020304210","Basma.tito@med.svu.edu.eg",{"type":30,"investigatorFullName":31,"investigatorTitle":32,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Soheir Abdelhamid","Soheir Abdel-Hamid, principle investigator","100558049",false,"NCT06546059","Gasdermin D Expression in Generalized Vitiligo Patients After Narrow-band Ultraviolet B Therapy","Inclusion Criteria:\n\n* Patients with stable vitiligo of 6 months duration,\n* Both sex and ages(10-75)\n\nExclusion Criteria:\n\n* pregnancy,\n* lactation,\n* patients under or previous phototherapy,\n* patients on other immunosuppressives,\n* patients receiving topical or systemic therapy like antioxidants and vitamins were kept off treatment for 2 weeks prior to recruitment into the study.",true,"ALL","10 Years","75 Years",{"count":43,"type":44},40,"ESTIMATED","INTERVENTIONAL",[47],"NA","The aim of this study is to:\n\n1. Evaluate the role of tissue Gasdermin D expression using immunehistochemstry techniques in patients with generalized vitiligo and compare it with healthy controls.\n2. Evaluation expression of tissue Gasdermin D using immunehistochemstry techniques in patients with generalized vitiligo after narrow band ultraviolet B therapy.\n3. Determine whether there is a relationship between Gasdermin D levels and disease duration and involved body surface area (VISA) in vitiligo patients.",[50],"Vitiligo, Generalized","NOT_YET_RECRUITING","2024-08-08",{"date":54,"type":55},"2024-08-09","ACTUAL",{"date":57,"type":44},"2024-08",{"date":59,"type":44},"2024-11",{"name":5,"class":6}]