[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100335553":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":12,"centralContacts":16,"locations":21,"responsibleParty":37,"collaborators":40,"id":45,"slug":7,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":7,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":51,"minAge":52,"maxAge":7,"enrollmentInfo":53,"targetDuration":56,"studyType":57,"phases":7,"briefSummary":58,"conditions":59,"keywords":64,"overallStatus":23,"whyStopped":7,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Medical College of Wisconsin","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Blood Collection","Blood will be collected via venipuncture and analyzed. Blood samples will be analyzed for HLA haplotype (a genetic sequence related to type 1 diabetes susceptibility), plasma-induced signature, diabetes autoantibodies, complete blood count with differential, and serum and plasma for storage. For family members with diabetes, blood will also be tested for A1c.",[13],{"name":14,"affiliation":5,"role":15},"Martin Hessner, PhD","PRINCIPAL_INVESTIGATOR",[17],{"name":14,"role":18,"phone":19,"phoneExt":7,"email":20},"CONTACT","414-955-4903","t1dinfo@mcw.edu",[22],{"facility":5,"status":23,"city":24,"state":25,"zip":26,"country":27,"countryCode":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"RECRUITING","Milwaukee","Wisconsin","53226","United States","US",{"type":30,"coordinates":31},"Point",[32,33],-87.90647,43.0389,{"lat":33,"lon":32},[36],{"name":14,"role":18,"phone":19,"phoneExt":7,"email":20},{"type":15,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Martin Hessner","Professor",[41,43],{"name":42,"class":6},"Benaroya Research Institute",{"name":44,"class":6},"Indiana University","100335553",false,"NCT03648918","Genetics Of Autoimmunity In Type I Diabetes","Inclusion Criteria (Families):\n\n* Families where at least one first-degree family member has type 1 diabetes\n* The diabetic proband in the family was diagnosed before the age of 39\n* Family members must be at least 2 years old to participate\n\nExclusion Criteria (Families):\n\n* Families with no history of type 1 diabetes\n* Families with a history of diabetes that is not type 1 (LADA, MODY, type 2 etc.)\n\nInclusion Criteria (Controls):\n\n* No family history of type 1 diabetes or other autoimmune conditions\n* Age 2 or older\n\nExclusion Criteria (Controls):\n\n* Personal or family history of autoimmune disease",true,"ALL","2 Years",{"count":54,"type":55},4000,"ESTIMATED","10 Years","OBSERVATIONAL","The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 diabetes. Scientists think that a person's own immune system, directed by genetic and environmental factors play a major role in its development. Participation involves a blood draw, a brief medical history questionnaire and measurements of height and weight. Some participants will be asked to return for annual follow-up visits for 10 years.",[60,61,62,63],"Type1diabetes","Diabetes Mellitus, Type 1","Type1 Diabetes Mellitus","Diabetes Mellitus",[65,66,67],"Family","Healthy Controls","Siblings","2026-03-12",{"date":70,"type":71},"2026-03-16","ACTUAL",{"date":73,"type":71},"2001-08",{"date":75,"type":55},"2050-01",{"name":5,"class":6},1]