Growth Hormone Resistance of Beta-cells A

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-45
SponsorUniversity of Missouri-Columbia

About this trial

The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with a personal history of gestational diabetes (high blood sugar in pregnancy) at the University of Missouri. The aim of the study is to advance understanding of how growth hormone affects beta-cells and risk factors for developing gestational diabetes.

Eligibility criteria

Qualifiers

Singleton, full term pregnancy within the past 5 years

Body mass index ≥18.5 kg/m2 and <45.0 kg/m2

Gestational Diabetes Group: History of gestational diabetes in the most recent pregnancy

Control Group: no history of gestational diabetes

Disqualifiers

Pregnant, planning to become pregnant during the study, or breastfeeding

Current diagnosis or history of type 1 or type 2 diabetes

Use of medications that can impact the study outcomes (e.g., GLP-1 receptor agonists)

History of bariatric surgery

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

30 Participants
are grouped into 2 trial groups