[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613666":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":22,"responsibleParty":45,"collaborators":10,"id":48,"slug":10,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":60,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":25,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Tongji Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Headache patients undergoing routine treatment",null,"Fifty thousand headache patients from several headache centers in China will be recorded to establish a headache database. Data collection includes epidemiological information, clinical data, neuroimaging, questionnaires, and real-world treatments. A cohort of 1,500 headache patients at Tongji Hospital's Neurology Department will receive blood and multi-model imaging collections. The patients will receive monthly interviews and undergo annual telephone follow-ups for 10 years. This cohort will contribute to establishing an integrated database system combining clinical, biological, and multi-omics data for precision medicine development in headache treatment.",[13,18],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Wensheng Qu Professor, DM PhD","CONTACT","+8618971622660","wsqu@tjh.tjmu.edu.cn",{"name":19,"role":15,"phone":20,"phoneExt":10,"email":21},"Han Zhang Dr, MD PhD","+8618627023031","523852566@qq.com",[23],{"facility":24,"status":25,"city":26,"state":27,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology","RECRUITING","Wuhan","Hubei","430030","China","CN",{"type":32,"coordinates":33},"Point",[34,35],114.26667,30.58333,{"lat":35,"lon":34},[38,41,43],{"name":39,"role":15,"phone":20,"phoneExt":40,"email":21},"Han Dr, MD PhD","+86-2783663337",{"name":42,"role":15,"phone":16,"phoneExt":40,"email":17},"Qu Professor, MD PhD",{"name":42,"role":44,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":44,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Wensheng Qu","Dr","100613666",false,"NCT07269561","Headache Registration and Followup Initiated by Tongji Hospital, HUST","HEALTH","Inclusion Criteria:\n\n* Meeting the diagnostic criteria for headache classification according to the International Classification of Headache Disorders 3rd edition (ICHD-3, 2018) Age between 6-70 years Voluntary participation with consent Good compliance with follow-up and questionnaire surveys\n\nExclusion Criteria:\n\n* Complex headache etiology, e.g., presence of ≥3 distinct factors causing headache Presence of severe systemic diseases or life expectancy less than 10 years Significant cognitive or psychiatric issues that prevent completion of questionnaire follow-ups and clinical assessments","ALL","6 Years","70 Years",{"count":58,"type":59},50000,"ESTIMATED","10 Years","OBSERVATIONAL","Headache is one of the most common chief complaints in clinical practice, with a high global prevalence rate. It may originate from a primary headache disorder or manifest as a clinical symptom of various diseases due to the complexity of its triggers, specific types, diagnosis, and treatment which present significant challenges. As people's life pace continues to accelerate and psychological and physiological pressures increase, many patients experience headache symptoms, leading to a growing number of patients seeking treatment in neurology departments. The increasing incidence of headache conditions has resulted in a decline in patients' quality of life.\n\nTherefore, this research is part of Hubei Province's major project \"Discovery and Functional Research of Major Disease Targets Based on Genetic Big Data.\" The study aims to establish a clinical cohort and develop a precise diagnosis and treatment system for headaches. This system will collect the history of headache sufferers, record the real-world treatment data, and incorporate sample banks, multi-dimensional databases, pre-clinical drug evaluation platforms, and clinical efficacy precise dynamic monitoring models through immunotherapy and other cutting-edge biotechnologies, multi-omics detection technologies, and big data bioinformatics analysis technologies.\n\nThe system will provide scientists and clinicians with auxiliary diagnostic and treatment decision support, offer reliable screening targets for early headache diagnosis and drug development companies, accelerate the latest headache diagnosis and targeted treatment, and achieve breakthrough advances in headache prevention and cure.",[64,65],"Headache","Comorbidities",[64,67,68,69,70],"prediction models","database","cohort","Real world observation","2025-11-26",{"date":73,"type":74},"2025-12-08","ACTUAL",{"date":76,"type":74},"2024-01-01",{"date":78,"type":59},"2028-12-31",{"name":5,"class":6},1]