[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634596":3},{"organization":4,"outcomesModule":7,"designInfo":83,"detailedDescription":87,"studyPopulation":88,"armGroups":89,"interventions":95,"overallOfficials":84,"centralContacts":100,"locations":106,"responsibleParty":125,"collaborators":127,"id":139,"slug":84,"hasResults":140,"nctId":141,"briefTitle":142,"officialTitle":143,"acronym":144,"eligibilityCriteria":145,"healthyVolunteers":146,"sex":147,"minAge":148,"maxAge":149,"enrollmentInfo":150,"targetDuration":153,"studyType":154,"phases":84,"briefSummary":155,"conditions":156,"keywords":164,"overallStatus":171,"whyStopped":84,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":181},{"fullName":5,"class":6},"University of Copenhagen","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":27,"otherOutcomes":46},[9,13,15,18,20,22,25],{"measure":10,"description":11,"timeFrame":12},"Omega-3 status","Eicosapentaenoic acid (EPA) in whole blood (% of total fatty acid)","One sampling point between April and August 2026",{"measure":10,"description":14,"timeFrame":12},"Docosahexaenoic acid (DHA) in whole blood (% of total fatty acid)",{"measure":16,"description":17,"timeFrame":12},"Micronutrient status","Vitamin D (total 25-hydroxyvitamin D) concentration in blood, nmol\u002FL",{"measure":16,"description":19,"timeFrame":12},"Hemoglobin concentration in blood (g\u002FdL)",{"measure":16,"description":21,"timeFrame":12},"Ferritin concentration in blood (µg\u002FL)",{"measure":23,"description":24,"timeFrame":12},"Inflammation status","C-reactive protein concentration in blood (mg\u002FL)",{"measure":23,"description":26,"timeFrame":12},"Alpha-1-acid glycoprotein concentration in blood (g\u002FL)",[28,32,34,36,39,43],{"measure":29,"description":30,"timeFrame":31},"Nutritional status","Height (cm)","One measurement between April and August 2026",{"measure":29,"description":33,"timeFrame":31},"Weight (kg)",{"measure":29,"description":35,"timeFrame":31},"Mid-upper arm circumference (cm)",{"measure":29,"description":37,"timeFrame":38},"Body mass index (kg\u002Fm\\^2)","Between April and August 2026",{"measure":40,"description":41,"timeFrame":42},"Hair stable isotopes ratio","Isotope ratios of δ13C and δ15N in hair sample","Between April 2026 to August 2026",{"measure":44,"description":45,"timeFrame":38},"Fish consumption","7 days recall, questionnaire",[47,50,53,56,60,63,67,69,71,74,76,79,81],{"measure":48,"description":49,"timeFrame":38},"Climate change perception and mitigation practice","Climate change and mitigation practice, questionnaire",{"measure":51,"description":52,"timeFrame":38},"Women empowerment","Women empowerment will be obtained using women empowerment assessment tool, questionnaire.",{"measure":54,"description":55,"timeFrame":42},"Dietary pattern, food frequency","Dietary pattern by food groups, questionnaire",{"measure":57,"description":58,"timeFrame":59},"Child omega-3 status","If a woman has a child aged 6-59 months, the child is assessed for EPA concentration in blood (% of total fatty acids).","One timepoint between April and August 2026",{"measure":57,"description":61,"timeFrame":62},"If the woman has a child aged 6 months to 5 years, the child is measured for DHA concentration in blood (% of total fatty acid)","One measure between April and August 2026",{"measure":64,"description":65,"timeFrame":66},"Micronutrient status, Child","If the woman has a child aged 6 months to 5 years, the child is measured for hemoglobin concentration in blood (g\u002FL)","April-August 2026",{"measure":64,"description":68,"timeFrame":12},"If the woman has a child aged 6 months to 5 years, ferritin concentration in blood (µg\u002FL), will be measured.",{"measure":64,"description":70,"timeFrame":12},"If the woman has a child aged 6 months to 5 years, Vitamin D (total 25-hydroxyvitamin D) concentration in blood, nmol\u002FL will be measured.",{"measure":72,"description":73,"timeFrame":12},"Inflammation status, Child","If the woman has a child aged 6 months to 5 years, the child's C-reactive protein concentration in blood (mg\u002FL) will be measured.",{"measure":72,"description":75,"timeFrame":12},"If the woman has a child aged 6 months to 5 years, alpha-1-acid glycoprotein concentration in blood (g\u002FL) will be measured.",{"measure":77,"description":78,"timeFrame":38},"Nutritional status, Child","If the woman has a child aged 6-59 months, the child's length\u002Fheight (cm) is measured.",{"measure":77,"description":80,"timeFrame":66},"If the women has a child aged 6-59 months, the child is measured for weight (kg)",{"measure":77,"description":82,"timeFrame":66},"If the woman has a child aged 6-59 months, the child is measured for MUAC (cm)",{"allocation":84,"interventionModel":84,"interventionModelDescription":84,"primaryPurpose":84,"observationalModel":85,"timePerspective":86,"maskingInfo":84},null,"COHORT","CROSS_SECTIONAL","Aquatic foods are fundamental to the Bangladeshi diet, providing nearly two-thirds of total animal protein. Despite this, malnutrition remains a severe public health crisis with a complex etiology. Bangladesh faces a double burden of malnutrition, marked by persistently high rates of micronutrient deficiencies affecting roughly half of both pregnant and non-pregnant women alongside rising levels of overweight and obesity. These challenges are further exacerbated by substantial intrahousehold inequities in this patriarchal society. Disempowerment and early marriage disproportionately expose adolescent girls and young women to inadequate nutrient intake and poor health outcomes, perpetuating an intergenerational cycle of malnutrition. Furthermore, chronic undernutrition and stunting continue to affect a large proportion of children under five.\n\nThe problem is particularly acute in coastal communities, where climate change impacts such as salinity intrusion and extreme weather compromise food production and dietary diversity. Understanding and improving the dietary and nutritional status of adolescent girls and young women is therefore essential to breaking the cycle of poor health and ensuring long-term population well-being. Building on a 2017 study conducted with a cohort of 240 adolescents, this research aims to provide longitudinal insights into how nutritional status, female autonomy, aquatic food consumption, and dietary practices have influenced the health and well-being of these women and their children nearly after 10 years.\n\nHypotheses\n\n1. Nutritional status, fish consumption, and female autonomy during adolescence (2017) influence the nutritional status of young women in 2026 and that of their offspring.\n2. Fish consumption is positively associated with biological markers (omega-3 fatty acids, vitamin D levels, and stable isotope ratios in hair).\n\nObjectives\n\n1. To assess changes in nutritional status, fish intake, socioeconomic factors, and female autonomy among young women from 2017 to 2026, and examine their associations with the nutritional status of their children (6 months-5 years).\n2. To investigate associations between assessed fish consumption and biological markers (omega-3, vitamin D, and stable isotope ratios in hair).\n\nThe study will be conducted in four distinct saline gradient agro-ecological zones across the shrimp-prawn farming regions of southwest Bangladesh, specifically in Fakirhat (Bagerhat District), Dumuria and Paikgacha (Khulna District), and Shyamnagor (Satkhira District).","The study population is 240 young women who were studied as adolescents in 2017, now young women aged 22-26 years. If they have child aged 6 months to 5 years, the youngest child is included.",[90],{"label":91,"type":84,"description":92,"interventionNames":93},"Follow-up of adolescent girls from 2017 to 2026","The cohort of adolescent girls enrolled in 2017 at ages 12-16 will be followed up in 2026 to assess changes in their socioeconomic status, nutritional status, dietary intake, and women empowerment, and to examine how these factors are associated with the nutritional status of their children aged 6 months-5 years.",[94],"Other: The follow-up aims to evaluate natural changes occurring from adolescence to young adulthood with respect to the study objectives due to lifestyle and environmental factors, without any intervention.",[96],{"type":6,"name":97,"description":98,"armGroupLabels":99,"otherNames":84},"The follow-up aims to evaluate natural changes occurring from adolescence to young adulthood with respect to the study objectives due to lifestyle and environmental factors, without any intervention.","There is no intervention",[91],[101],{"name":102,"role":103,"phone":104,"phoneExt":84,"email":105},"Nanna Roos, PhD","CONTACT","+45 3532 0829","nexs@nexs.ku.dk",[107],{"facility":108,"status":84,"city":109,"state":110,"zip":111,"country":112,"countryCode":113,"cosmosGeoPoint":114,"geoPoint":119,"contacts":120},"International Centre for Diarrhoeal Disease Research, Bangladesh (icddr, b)","Dhaka","Capital Region","1000","Bangladesh","BD",{"type":115,"coordinates":116},"Point",[117,118],90.40744,23.7104,{"lat":118,"lon":117},[121],{"name":122,"role":103,"phone":123,"phoneExt":84,"email":124},"Gulshan Ara, MSc","+8802982700110","gulshan.ara@icddrb.org",{"type":126,"investigatorFullName":84,"investigatorTitle":84,"investigatorAffiliation":84,"oldNameTitle":84,"oldOrganization":84},"SPONSOR",[128,131,133,135,137],{"name":129,"class":130},"Noakhali Science and Technology University","UNKNOWN",{"name":132,"class":130},"Bangladesh Agricultural University (BAU)",{"name":134,"class":6},"University of Stirling",{"name":136,"class":6},"University of Aberdeen",{"name":138,"class":6},"International Centre for Diarrhoeal Disease Research, Bangladesh","100634596",false,"NCT07541742","Health and Nutritional Outcomes Among Young Females and Children in Southwest Bangladesh","Health and Nutritional Outcomes Among Young Females and Children in Southwest Bangladesh: A Cohort Study","AQUAFOOD","Inclusion Criteria:\n\n* Young women aged 22-27 years who previously participated in the 2017 study. See study description.\n* If the women has a child age between 6 months to 5 years, the child child is included to be assessed\n\nExclusion Criteria:\n\n* Participants with serious health conditions that may interfere with study procedures or data collection.",true,"ALL","5 Months","27 Years",{"count":151,"type":152},240,"ESTIMATED","2 Years","OBSERVATIONAL","This study aims to examine how societal and climate changes influence the nutritional status and fish consumption of young women over a 10 year period in southern Bangladesh, and how these factors affect their children's health. A cohort of 240 adolescents first studied in 2017 will be followed to assess changes in their dietary patterns, nutritional status, climate perceptions and mitigation practices, as well as the nutritional status of their children aged 6 months to 5 years.\n\nThe study in 2017 sampled 60 adolescent girls in each of four rural communities, plus a semi-rural community around a fish processing plant, representing in total 5 communities. Of these 60 X 5 = 300 girls, the current study follows up the individuals in the rural communities representing a cohort of 240.\n\nBangladesh faces high rates of adolescent malnutrition, with many girls married before 18 and suffering from chronic nutrient deficiencies. These issues have long-term impacts on health, productivity, and intergenerational well-being. By linking the fisheries and aquaculture sector, a key to Bangladesh's economy with public health and nutrition, this research aims to guide targeted policies for vulnerable coastal communities.",[157,158,159,160,161,162,163],"Nutritional Status","Micronutrient Status","Omega 3 Fat Status","Diet Diversity","Markers of Inflammation","Climate Adaptation","Climate Change Awareness",[165,166,167,168,169,170,112],"Aquatic foods","adolescent nutrition","fish intake assessment","dietary biomarkers","climate adaptation","intergenerational nutrition","NOT_YET_RECRUITING","2026-04-30",{"date":174,"type":175},"2026-05-06","ACTUAL",{"date":177,"type":152},"2026-04-15",{"date":179,"type":152},"2026-12-10",{"name":5,"class":6},1]