High Resolution, High-speed Multimodal Ophthalmic Imaging

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Hospitalier National d'Ophtalmologie des Quinze-Vingts

About this trial

Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging. However, current clinical imaging systems are limited in resolution, speed, or access to certain structures of the eye.

The use of a high-resolution imaging system improves the resolution of ophthalmoscopes by several orders of magnitude, allowing the visualization of many microstructures of the eye: photoreceptors, vessels, nerve bundles in the retina, cells and nerves in the cornea.

The use of a high-speed acquisition imaging system makes it possible to detect functional measurements such as the speed of blood flow. The combination of data from multiple imaging systems to obtain multimodal information is of great importance for improving the understanding of structural changes in the eye during a disease.

The purpose of this project is to observe structures that are not detectable with routinely used systems.

Eligibility criteria

Qualifiers

People over 18

Patient with a pathology affecting the eye or healthy volunteer

Participant who signed the consent

Beneficiaries of the health insurance

Disqualifiers

Patients with a history of photosensitivity.

Patients who have just received a photodynamic therapy treatment (

Patients taking drugs with photosensitivity as a side effect.

Persons with pacemakers or other implanted electronic medical device

Trial design

Treatments tested in this trial

  • High-resolution retinal imaging through adaptive optics
  • High-resolution retinal imaging through holographic systems

Treatment groups

1,200 Participants
are divided into 1 treatment group