[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100093592":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":29,"responsibleParty":48,"collaborators":50,"id":53,"slug":10,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"NYU Langone Health","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Families with Hirschsprung Disease",null,"Individuals with Hirschsprung disease and their affected and unaffected relatives.",[13],"Other: Identification of genetic causes of Hirschsprung Disease",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Identification of genetic causes of Hirschsprung Disease","Blood, saliva, or DNA samples are requested from all study participants. The blood or saliva samples are used to isolate DNA in all participants. Blood samples are also used to establish cell lines in some participants.",[9],[20],{"name":21,"affiliation":5,"role":22},"Aravinda Chakravarti, PhD","PRINCIPAL_INVESTIGATOR",[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Jenna Pucel, MS, CGC","CONTACT","212-263-8069","jenna.pucel@nyulangone.org",[30],{"facility":31,"status":32,"city":33,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"New York University School of Medicine","RECRUITING","New York","10016","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-74.00597,40.71427,{"lat":41,"lon":40},[44,47],{"name":45,"role":26,"phone":27,"phoneExt":10,"email":46},"Monica Erazo, MS","Monica.Erazo@nyulangone.org",{"name":21,"role":22,"phone":10,"phoneExt":10,"email":10},{"type":49,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[51],{"name":52,"class":6},"New York University","100093592",false,"NCT00478712","Hirschsprung Disease Genetic Study","Genetic Analysis of Hirschsprung Disease","Inclusion Criteria:\n\n\\- Individuals with Hirschsprung disease and their first degree relatives (any segment length of disease, with or without other congenital anomalies or health problems, single or multiple affected individuals in family)\n\nExclusion Criteria:\n\n* Unable or unwilling to provide sample for genetic studies\n* Individual, parent, or guardian unable to comprehend and provide informed consent",true,"ALL","1 Week","100 Years",{"count":64,"type":65},3000,"ESTIMATED","OBSERVATIONAL","Hirschsprung disease is a genetic condition caused by lack of nerve cells in varying lengths of the intestines. This study will investigate the complex genetic basis of the disease, which involves multiple interacting genetic factors.",[69],"Hirschsprung Disease",[71],"Hirschsprung","2026-06-03",{"date":74,"type":75},"2026-06-04","ACTUAL",{"date":77,"type":75},"2001-01",{"date":79,"type":65},"2028-12",{"name":5,"class":6},1]