About this trial
The BRIGHT (Behavioral Rehabilitation Through Image-Guided Home-based Training) study aims to evaluate the effectiveness of image-guided, home-based perceptual training at improving visual performance in individuals with visual field loss.
Using a prospective, crossover design, BRIGHT combines visual behavioral testing, neuroimaging, and a home-based intervention. It aims to 1) identify neural pathways that support training-induced visual plasticity; and 2) compare the efficacy of different types of visual training delivered in a home-based setting.
Eligibility criteria
Qualifiers
At least 18 years of age.
Capable of providing informed consent and complying with study procedures.
Unilateral or bilateral focal brain damage causing visual field loss.
At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year.
Disqualifiers
Severe neurological or psychiatric conditions unrelated to the focal lesion that may interfere with study participation or data interpretation.
Current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5.
Ocular disease or disorder.
Trial design
Treatments tested in this trial
- High-level perceptual learning-based training
- Low-level perceptual learning-based training
Treatment groups
Sponsors and collaborators
Georgetown University
Lead sponsor
American Heart Association
Collaborator